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PREVALENCE AND ANTIBIOGRAM OF METHICILLIN RESISTANCE STAPHYLOCOCCUS AUREUS AT A TERTIARY CARE HOSPITAL IN JAIPUR, RAJASTHAN.

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author NameUniversity of Author
Abstract (2. Language): 
Aim: The aim of this study is to report the prevalence and antibiotic susceptibility of methicillin resistance Staphylococcus aureus in a tertiary care hospital, Jaipur, Rajasthan. Materials and methods: The study was conducted during February 2011 to March 2012 and the bacterial isolates from various clinical samples were cultured as per standard protocol and all 195 isolates of S. aureus obtained were included in the study. The antibiotic susceptibility test was performed by Kirby Bauer disc diffusion method as recommended by CLSI. The isolates were tested for methicillin resistance by oxacillin (1pig) disc diffusion method. Results: During a period of one year study, the prevalence of MRSA was found to be 46 (23.59%). High resistance to penicillin, erythromycin, cephalexin, norfloxacin and ciprofloxacin was observed, however low resistance to antibiotics amikacin, clindamycin, azithromycin and, gentamycin had been observed. 38 (82.6%) MRSA strains were observed to multidrug resistant (MDR). All 46 MRSA and 149 MSSA strain were sensitive to Vacomycin and Linezolid. Conclusion: The most effective way to prevent MRSA infections is by doing continuous surveillance of antibiotic resistance profiles of local S. aureus isolates to formulate antibiotic policies. This may also help in preventing the spread of multidrug resistant strains
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REFERENCES

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