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SPHINGOSOMES: A NOVEL VESICULAR DRUG DELIVERY SYSTEM

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Sphingosomes is bilayered vesicles in which an aqueous volume is entirely enclosed by membrane lipid bilayer mainly composed of natural or synthetic sphingolipid. Sphingosomes solve the major drawback of vesicle system (liposomes, niosomes) like less stability, less in vivo circulation time, low tumor loading efficacy in case of cancer therapy. The outcome of this review is that sphingosomes represents a promising vesicular drug delivery system to delivers therapeutic compounds for a range of possible application.
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  • 2
305-312
  • English

REFERENCES

References: 

1. Robinson JR, Lee VHL. Controlled drug delivery: Fundamentals and Applications. 2nd ed., Informa healthcare; Vol 20: 56-57.
2. Molema G, Meijer DKF. Drug Targeting Organ-Specific Strategies. Wiley-VCH Verlag
GmbH, 2001.
3. Shah Adarsh A et al. Organelle Specific Targeted Drug Delivery- A Review. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2011; 2(3):895-912.
4. Shailza Singh et al. Molecular drug targets and structure based drug design: A holistic approach. Bioinformation. 2006; 1(8): 314-320.
5. Schreier H. Drug Targeting Technology: Physical, Chemical, Biological Methods. Marcel Dekker, 2001.
6. Gupta Manish, Sharma Vimukta. Targeted drug delivery system: A Review.
Available Online At www.ijprbs.com
Research Article
Ashok K, IJPRBS, 2013; Volume 2(2): 305-312
Research Journal of Chemical Sciences.
2011; 1(2): 135-138.
7. Biju SS, Sushama Talegaonkar, Mishra PR, Khar RK. Vesicular systems: An Overview. Indian Journal of Pharmaceutical
Sciences. 2012, Jun 28; IP: 117. 211.123.49
8. Ravi Kumar, Shivjee Kumar, Shyam Shankar Jha, Amit Kumar Jha. Vesicular System- Carrier for Drug Delivery. Der Pharmacia Sinica. 2011; 2(4):192-202.
9. Stuti Gupta, Ravindra Pal Singh, Priyanka Lokwani, Sudhir Yadav, Shivjee KG. Vesicular system as targeted drug delivery system: An overview. International journal of pharmacy and technology. 2011; 3: 987¬1021.
10. Mayank Gangwar, Ragini Singh, Goel RK, Gopalnath. Recent Advances in various emerging vesicular system: An Overview. Asian Pacific Journal of Tropical Biomedicine. 2012:1-4.
11. Jain NK. Controlled and Novel Drug Delivery. 1st ed. CBS Publishers and Distributors, New Delhi, 2001.
ISSN: 2277-8713
IJPRBS
12. Vyas SP, Khar RK. Targeted and controlled drug delivery. CBS publisher and Distributor, New Delhi, 2001.
13. Swarnalatha Saraf, Paliwal S, Shailendra Saraf. Sphingosomes A novel approach to vesicular drug delivery. International Journal of current scientific research, 2011; 1(1):63-68.
14. Webb MS, Bally MB, Mayer LD.
Sphingosomes for enhanced Drug Delivery. United States Patent. 5, 543, 152, Aug. 6, 1996.
15. Webb MS, Bally MB, Mayer LD, Miller JJ, Tardi PG. Sphingosomes for enhanced drug delivery. United States Patent. 5,741,516, Apr. 21, 1998.
16. Muller et al. Drug delivery vehicles and uses thereof. European Patent. 1 537 858
A1, 2005.
17. Webb MS, Bally MB, Mayer LD, Miller JJ, Tardi PG. Sphingosomes for enhanced drug delivery. United States Patent. 5,814,335, Sep. 29, 1998

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