You are here

LONG TERM EXPOSURE TO CHEMICALS, INSECTICIDES AND HEAVY METALS CAUSING TOXICITY: A REVIEW

Journal Name:

Publication Year:

Author Name
Abstract (2. Language): 
Insecticides are used worldwide for crop protection especially in the developing nations. Neonicotinoid insecticides, which are one of the most important classes of commercial insecticides worldwide are systemic in plants and animals and are used to manage crop pests and control fleas on cats and dogs. Acetamiprid belongs to the class of chloronicotinyl neonicotinoid insecticides used to control insects and ectoparasites viz., Hemiptera, particularly aphids, thysanoptera and leptoptera on a wide range of crop species. The indiscriminate and injudicious use of second generation fluoroquinolones viz., enrofloxacin produced anemia, leucopenia, hypoglycaemia, hypoproteinemia, increased enzymatic activity and hepatotoxic and nephrotoxic effects in broiler chickens. Exposure to heavy metals results in congestion and hemorrhages in the lungs, tubular degeneration in kidneys and occasional hemorrhages in the brain. The present article was conducted to review the various pharmaceutical, physiological and toxicopathological effects of different chemical agents and heavy metals due to environmental exposure and through feed on poultry birds. Heavy metals possess high density and toxicity towards living beings. Heavy metals like arsenic, chromium, lead and mercury are point popular and relevant. Heavy metals constitute the crust of the earth which resists degradation. Human get inflicted with heavy metals through the agency of food, water and atmosphere. Mercury poisoning by eating fishes is a prominent cause for public health hazard.
FULL TEXT (PDF): 
333-342

REFERENCES

References: 

1. Singh TB, Mukhopadhayay SK, Sar TK, Ganguly, S Acetamiprid induces toxicity in mice under experimental conditions with prominent effect on the hematobiochemical parameters. J Drug Metab Toxicol 2012;3(6): 1-5, 134. doi:10.4172/2157-7609.1000134.
2. Ganguly S. Effect of induced toxicopathological effect of pharmaceutical agents and heavy metals on broiler birds: A Review. Int
Available Online At www.ijprbs.com
Review Article
Subha Ganguly, IJPRBS, 2013; Volume 2(3): 333-342
ISSN: 2277-8713
IJPRBS
Res J Pharm 2013a;4(5): 24-25.
DOI/CrossRef Prefix: 10.7897/2230¬8407.04507.
3. Paul A, Mukhopadhayay SK, Ganguly S, Pal S, Niyogi D. Study on induced enrofloxacin toxicity in broiler birds. Int J Adv Innov Res 2013;2(5): 675-79.
4. Kumar D, Mukhopadhayay SK, Ganguly S, Niyogi D, Jana S, Pal S. Effect of acute selenium toxicity in broiler birds. Int J Adv Innov Res 2013;2(5): 680-82.
5. Ganguly S. Human health benefits from fish consumption and environmental
toxicity issues in fish flesh. Int Res J Biol Sci 2013b;In press.
6. Flanner KDP, Aucoin, Whitt DA, Pras SA. Plasma Concentration of Enrofloxacin in African grey parrots.
Avian Dis 1990;34:1017-22.
7. Zhou S, Wang D. Study on acute toxicity of norfloxacin nicotinate in chickens. J HAU Agril Univ
1994;13(1):80-83.
8. Sharma AK, Khosla R, Kela AK, Mehta VL. Fluoroquinolones: Antimicrobial agents of the 90's. Indian J
Pharmacol 1994;26:249-61.
9. Niyogi D. Toxicopathology and immune response of broiler chickens induced with ciprofloxacin toxicity, 1999;M.V.Sc thesis submitted to West Bengal University of Animal and Fishery Sciences, India.
10. Sugawara
T
, Yoshida M, Takada S, Miyamoto M., Nomura M. One month oral toxicity study of the new quinolone Antibacterial agent in rats and cynomalgus monkeys. Arzneimitted forschung 1996;46(7):705-10.
11. Niyogi, D, Mukhopadhayay SK, Ganguly S. Bioavailability of arsenic in chronic induced arsenic toxicity in
broiler birds. Indian Vet J 2013;90(6): 23-25
12. Salyi G, Banhidi G, Szabo E, Gonye S, Ratz F. Acute selenium poisoning in broilers. Magy Allatorv Lap 1993;48:22-26. (Vet Bull 64:2969).
13. Khan MZ, Szarek J, Markiowicz, K. Concurrent oral administration of
Available Online At www.ijprbs.com
Review Article
Subha Ganguly, IJPRBS, 2013; Volume 2(3): 333-342
monensin and selenium to broiler chickens : effects on concentrations of different elements in the liver. Acta Vet
Hung 1993a;41: 365-79. (Nutr Abstr Rev 64: 4790).
14. Khan MZ, Szarek J, Krasnodebska-Depta A, Konicicki A. Effect of concurrent administration of lead and selenium on some haematological and biochemical parameters of broiler chickens. Acta vet Hung 1993b;41:123-
37 (Nutr Abstr Rev 64: 5060).
15. Rosenfeld I, Beath OA. Selenium. Geobotany, Biochemistry, Toxicity and Nutrition. Academic Press, New York,
1964.
16. Cousins FB, Cairney IM. Some aspects of selenium metabolism in
sheep. Flust J Agr Res 1961;12:927-42.
[cited by Shamberger. 1983].
17. Mondal S. Studies on the toxicopathology of acetamiprid in rats. MVSc Thesis submitted to College of Veterinary Science and Animal Husbandry, Indira Gandhi Krishi Vishwavidyalya, Durg, India. 2007.
ISSN: 2277-8713 IJPRBS
18. Bhardwaj S, Srivastava MK, Kapoor U, Srivastava LP. A 90 days oral toxicity of Imidacloprid in female rats: morphological, biochemical and histopathological evaluations. Food and Chem Toxicol 2010;48(5): 1185-90.
19. Goyal BS., Garg SK, Garg BD. Effect of low levels of malathion administration on blood glucose erythrocytes concentration in WLH chiks. Indian J Poult Sci 1986; 21: 156¬58.
20. Zhang Jiao-Jiao, Wang Yi, Xiang Hai-Yang, Li Meng Xue, Li Wen Hao, Ma Kai Ge, Wang Xian- Zhong and Zhang Jia-Hua. Oxidative stress: Role in acetamiprid induced impairment of the male mice reproductive system. Agricultural Sciences in China
2010;10(5), 786-96.
21. Ganguly S. A Handbook on Basic and Clinical Toxicology of Livestock, Birds and Fishes. Research India Publications, Delhi, India. 2013c;Book Proposal Accepted. ISBN xxx-xxxx-xxx-xxx. In press.

Thank you for copying data from http://www.arastirmax.com