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IN VITRO ANTIOXIDANT ACTIVITY OF AMORPHOPHALLUS PAEONIIFOLIUS (DENNST.) NICOLSON VAR. CAMPANULATUS (BLUME EX.DECNE) SIVADASAN

Journal Name:

  • The International Journal of Pharmaceutical Research and Bio-Science

Publication Year:

  • 2013

Key Words:

Author Name
Abstract (2. Language): 
Antioxidant activity of petroleum ether, benzene, ethyl acetate, methanol and ethanol extracts of the corm of Amorphophallus paeoniifolius have been tested using various antioxidant model systems viz., DPPH, hydroxyl, superoxide, ABTs and reducing power. The methanol extract of corm showed potent in vitro antioxidant activities. Ethanol extract of the plant showed strong DPPH radical scavenging activity. The maximum inhibitory concentration (IC 50) in all models viz, superoxide, DPPH, ABTs and hydroxyl radical were found to be 83.14, 34.50, 31.44 and 19.56μg/ml respectively at 1mg/ml concentration. The findings of the present study confirmed the presence of total phenolics and flavonoids and possess in vitro antioxidant activity.
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REFERENCES

References: 

1. Vallo M, Rhodes CJ, Moncol J, Izaleovic M
and Mazar M. free radicals, metals and
antioxidants in oxidative stress- induced
cancer. Chem Biol Interact. 2006; 160:1-40.
2. Adephapol AA, Jimoh FO, Afolayan AJ
and Masika PJ. Antioxidant properties of
the methanol extract of the leaves and
stems of Celtis Africana. Rec Nat Prod 2009;
3:23-31.
3. Rajkumar V, Guha G and Kumar RA.
Antioxidant and anti-neoplastic activities of
Picorhiza kurroa extracts. Food Chem
Toxicol. 2011; 49:363-369
4. Lim YY and Murtijaya J. Antioxidant
properties of Phyllanthus amarus as
affected by different drying methods.
Lebensm – Wiss. Technol. 2007; 40:1664-
1669.
5. Lalitharani S, Kalpana devi V, Tresina
Soris P, Maruthupandian A and Mohan V.R.
Ethnomedicinal plants used by Kanikkars of
Agasthiarmalai Biosphere Reserve,Western
Ghats. J. of Ecobiotech. 2011; 3:16-25
6. Lachman J, Hamouz K, Orsak M and Pivec
V. Potato tubers as a signfcant source of
antioxidant human nutrition. Rostl. Vyr.
2000; 46: 231-236.
7. Eom SH, Cheng WJ, Hyoung JP, Kim EH,
Chung MI, Kim MJ, Yu CY and Cho DH. Far
infra red ray irradiation stimulates
Research Article CODEN: IJPRNK ISSN: 2277-8713
Mohan VR, IJPRBS, 2013; Volume 2(5):211-222 IJPRBS
Available Online at www.ijprbs.com
221
antioxidant activity in Vitis flexuosa Thunb.
Berries. Korean J. Med. Crop. Sci. 2007; 15 :
31-323
8. Blois M.S. Antioxidant determination by
the use of a stable free radical. Nat 1958;
181: 1199-1200.
9. Halliwell B, Gutteridge JMC and Aruoma
OI. The deoxyribose method: a simple test
to be assay for determination of rate
constants for reaction of hydroxyl radicals.
Ana Biochem 1987; 165: 215-219.
10. Robak J and Gryglewski RJ. Flavonoids
are scavenges of superoxide anions.
Biochem. Pharmacol 1988; 37:837-841
11. Re R, Pellegrini N, Proteggente A,
Pannale A, Yang M and Rice- Evans C.
Antioxidant activity applying an improved
ABTs radical cation decolorization assay.
Free Radical Bio. Med. 1999; 26: 1231-1237.
12. Singh R, Singh B, Singh S, Kumar N,
Kumar S and Arora S. Investigation of ethyl
acetate extract/fractions of Acacia nilotica
wild. Ex. Del as potent antioxidant. Re Nat
Prod 2009; 3: 131-138.
13. Oyaizu M. Studies on product of
browning reaction prepared from glucose
amine, Jap J Food Chem 1986; 44: 307-315.
14. Jorgensen LV, Madsen HL, Thomsen MK,
Dragsted LO and Skibsted LH. Regulation of
phenolic antioxidants from phenoxy
radicals: An ESR and electrochemical study
of antioxidant hierarchy. Free Radical Res
1999; 30: 207-220.
15. Arts IC and Hollman PC. Polyphenols
and disease risk in epidemiological studies.
Am J Clin Nutr 2005; 81: 317S-325S
16. Scallbert A, Manach C, Morand C,
Remesy C and Jimenez L. Dietary poly
phenols and the prevention of disease. Crit
Rev Food Sci Nutr 2005; 45: 287-306.
17. Cushnie TPT and Lamb AJ. Antimicrobial
activity of flavonoids. Int J Antimicrob
Agents. 2005; 26:343-356.
18. De Sousa RR, Quiiroz KC, Souza AC,
Gurgueira SA, Augusto AC and Miranda MA.
Phosphoprotein levels, MAPK activities and
NFKappaB expression are affected by
fisetin. J Enzyme Inhib Med Chem 2007; 22:
439-444.
19. Basma AA, Zakania Z, Latha L and
Saridhasan S. Antioxidant activity and
phytochemical screening of the methanol
extracts of Euphorbia hirta L. Asian Pac J
Trop Med 2011; 4: 386-390.
20. Battu CR, Ethadi SR, Vede PG, Swathi PK,
Chandrika K, Rao VA et al. Evaluation of
antioxidant and anti-inflammatory activity
of Euphorbia heyneana Spreng. Asian Pac J
Trop Biomed 2011; $191-$194.
21. Naskar S, Islam A, Mozumdes UK, Saha
P, Haldar PK, Gupta M. et al. In vitro and in
vivo antioxidant potential of
hydromethanolic extract of Phoenix
dactylijera fruits. J Sci Res 2010; 2:144-157.
22. Mbaebie BO, Edeoga HO and Ajelayan
AJ. Phytochemical analysis and antioxidant
activities of aqueous bark extract of Schoba
Research Article CODEN: IJPRNK ISSN: 2277-8713
Mohan VR, IJPRBS, 2013; Volume 2(5):211-222 IJPRBS
Available Online at www.ijprbs.com
222
lahtolic Jacq. Asian Pac J Trop Biomed.
2012; 118-124.
23. Dub PD, Tu YY and Yen GC. Antioxidant
activity of water extract of Harng Iyur
(Chrysabthemum moifolium Ramat).
Lebensm-Wiss Technol 1999; 32: 269-277.
24. Gordon MH. The mechanism of the
antioxidant action in vitro. In: Food
antioxidants. Hudson BJF (ed).London.
Elsevier. 1990; pp1-18.

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