Journal Name:
- International Journal of Science and Engineering Investigations
Abstract (2. Language):
Devic’s neuromyelitis optic is an inflammatory disease of the central nervous system characterized by the combination of episodes of extensive myelitis and optic neuritis. It is an autoimmune disease which has been long time confused with a particular form of multiple sclerosis (MS), which is currently known to be due to the presence of anti-aquaporin-4 autoantibodies (AQP4) called antibodies anti-NMO.
We report the diagnostic difficulties seen in a black female patient presenting a clinical picture of optico-medullary involvement evolving for a decade and meeting the diagnostic criteria of Devic's disease: medullary MRI has confirmed extensive spinal cord injury in more than three segments. The study of CSF showed pleocytosis without oligoclonal band. The anti-NMO- antibodies were positive.With the use of MRI and the dosage of anti-NMO antibodies, Devic's neuromyelitis optica could be diagnosed early. Evolution is often pejorative that can lead to blindness and severe motor sequelae
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FULL TEXT (PDF):
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