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PERİAPİKAL LEZYONLU KİŞİLERDE ENDOTELİN DÜZEYLERİ

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 1998

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Endothelin Levels in the Patients with Periapical Lesions. Periapical lesions are one of Ihe most imporlant topic in the field of mouth and jaw diseases and surgery. They are the pathological formations which occur as a result of physical, chemical, microbiological and immunological stimulations on the periapical area. Some of the studies showed that prostaglandins have played an imporlant role on the periapical lesions. Like prostaglandings endothelin is also a local mediator. This study has been planned for the aim of invesligating urinary endothelin levels in patients with periapical kesions compared with control group.For the estimation of endothelin levels Endothelin (125I)(Eurodiagnostica, UK) kit was ıısed. When the endothelin levels of control (5.15+2.7 pmol/1) and study (5.77±2.5 pmol/1) groups vveıe compared, no imporlant change was found. As a conclusion, it could be said that urinary excretion of endothelin has not changed signifıcantly in the patients with periapical lesions
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Abstract (Original Language): 
Ağız ve çene hastalıkları ve cerrahisinin önemli konularından birini oluşturan periapikal lezyonlar birçok fiziksel, kimyasal, mikrobiyolojik ve immünolojik uyarıların periapikal bölgeyi uyarması sonucu meydana gelen patolojik oluşumlardır. Yapılan bazı çalışmalarda prostaglandinlerin de periapikal lezyonların üzerinde önemli rol oynadıkları gösterilmiştir. Prostaglandinler gibi lokal bir mediatör olan endotelinin idrardaki düzeylerinin periapikal lezyonlu kişilerde kontrol grubuna göre değişip değişmediğini araştırmak üzere bu çalışmada düzenlendi. Endotelin tayini için Endothelin (1251) (Euıodiagnoslica, UK) kiti kullanıldı. Deney grubu (5.77+2.5 pmol/1) ve kontrol grubu (5.15±2.7 pmol/1) endotelin düzeyleri birbiri ile kıyaslandıu ğında, istatistiksel yönden bir fark bulunmadığı saptandı. Sonuç olarak idrar ile endotelin salgılanırının periapikal lezyonlu kişilerde kayda değer bir değişiklik göstermediği söylenebilir.
FULL TEXT (PDF): 
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  • 4
466-468
  • Turkish

REFERENCES

References: 

KAYNAKLAR
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