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KRONIK IDIYOPATIK TROMBOSİTOPENİK PURPURA VE BÜLLÖZ PEMFİGOİD BİRLİKTELİĞİ: OLGU SUNUMU

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2002

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Siımdtaneoıts occuırence of immune tyhrombocytopenic purpura and bullous pemphigoid: a cose report. Otoimmune diseases develop due to disordered regulation in immune tolerence. In a patient who had developed disorder an autoimmune disorder, the chance of developing another autoimmune disorder is higher than in normal population. In this paper we report a ca-se who had both autoimmune idiopathic thrombocytopenic purpura and bullous pemphigoid simultaneously. A 45-year-old female was admitted to the hospital with complaints of itching and blistering on hands, easy bruising, and hypermenorrhea. idiopathic thrombocytopenic purpura was diagnosed by medical history, physical examination, peripheral blood smear and bone marrow aspiration, and bullous pemphigoid was confirmed by skin biopsy and immunoglo-bulin deposition in basal membrane of epidermis. Both diseases responded well to steroid tre-atment.
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Abstract (Original Language): 
Otoimmün hastalıklar, immun toleransın bozulması sonucu gelişirler. Herhangi bir otoimmun hastalığı olan bir kişide, beraberinde başka bir otoimmun hastalığın ortaya çıkma ihtimali yüksektir. Bu yazıda idiyopatik otoimmun trombositopeni ve büllöz pemfigoidin birlikte ortaya çıktığı bir olgu sunulmaktadır. Kırkbeş yaşındaki kadın hasta bir yıldan beri ellerde kaşıntı ve su toplanmaları, 6 aydır ise hipermenore ve küçük travmalarla kolay morarma şikayetleri ile başvurdu. Fizik muayene, periferik yayma ve kemik iliği aspirasyonu yapılıp trombositopeni yapan diğer nedenler dışlanarak idiyopatik otoimmun trombositopeni tanısı; deri biyopsisi ve bazal membranda antikor birikimi ile de büllöz pemfigoid tanısı konuldu. Her iki hastalık da steroid tedavisine iyi cevap verdi.
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  • 1
78-81
  • Turkish

REFERENCES

References: 

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