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PREEKLAMPTİK HASTALARDA İNTRAKRANTAL KANAMA İÇİN MATERNAL RİSK FAKTÖRLERİ VAR MI?

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Abstract (2. Language): 
Do maternal riskfactors existfor intracranial İtemorrhage in pveeclamptic potients? The aim of the study is to search the maternal risk factors for intracranial hemorrhage in preeclamptic patients. Cranial imaging findings of eighty-six patients with severe preeclanıpsİa, eclampsia and/or HELLP syndrome, who were encountered al Perinatology Department bctween January 1998 and December 2001, are presented in fhis study. Five patients witlı intracranial hemorrhage are comparcd with other patients for maternal age, gestational age, initial blood pressure, symptomatology, neurological findings, livcr enzymes and coagulation parameters. Patients with İntracranial hemorrhage were found to have statisticaily higher maternal age, blood pressure, symptom and neurological findings, Hver enzymes, FDP Ievels but Iower gestational age, platelet and fibrinogen ievcîs, when compared with other patients (p<0.05). Preeclamptic patients wİth higher matemal age, blood pressure, [iver enzymes, FDP Ievels, symptom and neurological findings ratio and lower gestational age, platelet and fibrinogen Ievels shoııld be care-fully evaluated for intracranial hemorrhage
Abstract (Original Language): 
Çalışmanın amacı preeklamptik hastalarda intrakranial kanama İçin maternal risk faktörlerini araştırmaktır. Ocak 1998-Arahk 200 İ tarihleri arasında ağır preeklampsi (n=23), eklampsi (n=26), HELLP sendromu (n=22), HELLP sendromu + eklampsi (n=15) tanısı alan 86 hastanın kranial görüntülemesi yapıldı. İntrakranial kanama saptanan 5 hasta diğer hastalar ile semptom, nörolojik bulgu, yaş, giriş tansiyonu, gebelik haftası, trombosit, transaminaz değerleri ve koagülasyon parametreleri açısından kıyaslandı. İntrakranial kanaması olan 5 hastada anne yaşı, giriş tansiyonu, transaminaz ve FDP değerleri diğer gruba göre anlamlı olarak yüksek, gebelik haftası trombosit değerleri ve fibrinogen seviyesi anlamlı olarak düşük saptandı (p<0.05). PT ve APTT değerleri arasında saptanan fark istatistik! olarak anlamlı değildi (p>0.05). Preeklamptik hastalarda ileri anne yaşının, yüksek tansiyonun, yükselmiş karaciğer enzimlerinin, erken gebelik haftasının, trombositopeninin ve bozulmuş koagülasyon parametrelerinin İntrakranial kanama açısından risk oluşturduğu sonucuna varıldı
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REFERENCES

References: 

1. Brovvn CEL, Purdy P, Cunnmgham FG: Head compuled tomography seans in wom.cn with cclampsia. Am J Obs-tetGyneeol 159:915 (1988).
2. Cunningham FG, Twicker D: Cerebral edema complica-ting eclampsia. Am J Obstet Gynecol J Obstet Gyneco! 182:94 (2000).
3. Dahmus MA, Barlon JR, Sibai BM: Cerebral imagirıg in eclampsi: magnetic resonance imagîng versus compuled tomography. Am J Obstet Gynecol 167:935 (1992).
4. Digre KB, Vamer MW, Osborn AG, Crawford S: Cranial magnetic resonance imaging of in severe preeclampsia versus eclampsia. Arch Ncurol 50:399 (1993).
5. Drislane FW, Wang AM: Muİtifocal cerebral hemorrhage in eclampsia and severe prc-cclampsia. J Ncurol 244:194(1997).
6. Friesc S, Fetter M, Küker W: Extensive brainstem edema in eclampsia: diffusion weighted MRI may indicate favo-rable prognosis. J Neurol 247:465 (2000).
7. Kaufman HH, Hui KS, Mattson JC ve ark: Cİİnicopatho-logical correlatıons of disseminalcd inlravascular coagu-lalion in patients with head İnjury. Ncurosurgcry 15:34 (1984).
8. Leduc L, Whecler JM, Kirshon B, Mitchell P, Colton DB: Coagulation profile in severe preeclampsia. Obstet Gynecol 79:14(1992).
9. Letsky EA: Disseminated intravascular coagulation. Best Pract Res Clin Obstet Gynaecol 15:623 (2001).
10. Lopez-Lera M, Liares MR, Heraandez Horta: Maternal mortality rates in eclampsia. Am J Obstet Gynecol 124: 49 (1976).
11. Porapakkham S: An epidemiologic study of cclampsia: Observation from 67 recent cases. Obstet Gynecol 58:609(1979).
12. Richards A, Moodley J: Active management of the un-conscious eclamptic patient. British Journal of Obstetrics and Gynecology 93:554 (1986).
13. Richards A, Graham D, Bullock R: Clinicopathological study of neurological complications due to hyperteıısive disorders of pregnaney. Journal of Neurology, Neurosur-gery, and Psychiatry 51:416 (1988).
14. Sameshima H, Nagaya K: intracranial hemorrhage as a cause of maternal mortality during 1991-1992 in Japan : A report of the Confidential Iııquiry in to maternal deaths Research Group in Japan. Br J Obstet Gynaecol 106:1171 (1999).
15. Sanders TG, Cayman TA, Sanches-Ramos L et al: Brain in eclampsia: MR imaging with clinical correlation. Ra-diology 180:475 (1991).
16. Sibai BM, Spinnato JM, Watson DL, Anderson GD: Eclampsia. IV. Neurologic findings and future outeome. Am J Obstet Gynecol 152:184(1985).

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