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PREMATÜRE OLGULARIN OKUL ÇOCUKLUĞU DÖNEMİNDEKİ AKCİĞER FONKSİYON TESTLERİ VE BRONŞ HİPERREAKTİVİTESİ

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Lung funetion tests and bronehial hyperreactivity of prematüre cases at the school age. This study w as planned with objecüve of determining long lasting lung sequela and existence of bronehial hyperreactivity in children with prematüre birth history and investigating their causes. The study was carried out at neonotology division of pediatry department at istanbul Dniversity Mcdicine Faculty through observation of 27 prematüre case group with birth weight below 2000 grams and gestatİon age under 37 months betwcen 1985 and 1989. Tlıe control group was com-posed of 24 healthy children at the ages ranging from 6 and 10 years old who wcre born matine. In order to deteımine bronehial hyperreactivity, lung funetion test with spironıetcr and cxercise provocation test in the form of fast run for 6 minutes were applied to ali cases. Neither neonatal respiration illness was observed nor respiratİon support was needed in any of the 27 prematüre case group. During our study, İt was noted rhat while forced vital capacity of our prematüre cases was preserved, their forced expİratory flow indexcs werc found low. The FEF 25-75, FEF 25, FEF50, FEF 75 and PEF values of our prematüre cases wcre found to be signİficantly low compared to the control group (p<0.05). Among the risk factors, prematüre birth, female sex, atopy and-environmental influences (smoking during pregnaney) wcre poİnted out as important. BHR was deteeted at the rate of 22% in the prematüre case group versus 4% in the control group. Despite bcing statİstically insİgnificant, the BHR was deteeted at a higher rate in the prematüre case group than in the control group. In conelusion, it was observed that airway funetion of the prematüre case group diminished in comparison with the control group in our study. The most important risk factor was designated as prematüre birth.
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Abstract (Original Language): 
Bu çalışma prematüre doğum öyküsü olan çocukların uzun süreli akciğer sekellerini belirlemek ve bronşial hiperreaktivite varlığını saptamak, bunların nedenlerini araştırmak amacıyla planlanmıştır. Çalışma İstanbul Üniversitesi İstanbul Tıp Fakültesi Çocuk Sağlığı vc Hastalıkları Anabilim Dalı Neonatoloji Bilim dalında 1985-1989 yılları arasında izlenen, doğum tartısı <2Ö00 gr., gestas-yon yaşı <37 hafta olan 27 prematüre olgu grubu ile gerçekleştirilmiştir. Kontrol grubunu ise ilkokul taramalarında seçilen, miadında doğum öyküsü olan, yaşları 6-10 yaş arasında dağılım gösteren 24 sağlıklı çocuk oluşturmuştur. Bronş hiperreaktivitesini saptamak için tüm olgulara spi-rometri ile akciğer fonksiyon testleri ve 6 dakika lıızlı koşu şeklinde uygulanan egzersiz provokasyon testi uygulanmıştır. 27 prematüre olgu grubunun hiçbirinde neonatal solunum hastalığı olmayıp solunum desteği ihtiyacı duyulmamıştır. Çalışmamızda prematüre olgularımızın zorlu vital kapasiteleri korunurken zorlu ekspiıatuar akım indeksleri daha düşük bulunmuştur. Prematüre olgularımızda FEF25-75, FEF25, FEF50, FEF75 ve PEF değerleri kontrol grubuna oranla anlamlı olarak düşük bulunmuştur, Risk faktörleri arasında prematüre doğum, kız cinsiyet, atopi, çevresel etkiler (annenin hamilelikte sigara içimi) önemli etkenler olarak gösterilmiştir. BHR ise prematüre olgu grubunda %22, kontrol grubunda ise %4 oranında saptanmıştır. BHR prematüre olgu grubunda istatistiki olarak anlamlı olmamakla birlikte daha fazla oranda bulunmuştur. Sonuç olarak, bizim çalışmamızda prematüre olgu grubunun kontrol grubuna oranla havayolu fonksiyon 1 arının azaldığı gözlenmiştir. En önemli risk faktörünün prematüre doğum olduğu belirtilmiştir.
FULL TEXT (PDF): 
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  • 2
78-84
  • Turkish

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