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FAZLA KİLOLU VE ŞİŞMAN KADINLARDA BOY UZUNLUĞUNUN RİSK GÖSTERGELERİ İLE İLİŞKİSİ

THE RELATIONSHIP BETWEEN HEIGHT MEASUREMENT AND METABOLIC RISK MARKERS IN OVERWEIGHT AND OBESE WOMEN

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2005

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
ABSTRACT Objective: The aim of this study was to determine the relationship between height and cardiovascular risk markers in overweight and obese women. Materials and methods: The study group was composed of 3665 overweight or obese women with body mass index varying from 25 to 67 kg/m2. In order to determine the relationship between body height and various cardiovascular risk markers, ANOVA, unpaired-t test and chi-square tests were performed. Results: Data analyses indicated a significant positive relationship between height and weight and HDL cholesterol and an inverse relationship between height and age, serum total cholesterol, glucose, triglyceride, systolic and diastolic blood pressure. No significant relationship was found between height and uric acid, insulin and HOMA (homeostasis model assessment). Age, weight, body mass index, glucose, cholesterol, triglyceride, systolic and diastolic blood pressures were found to vary between quartiles of stature. The incidence of diabetes mellitus, hypertension, hypercholesterolemia and abdominal obesity also was found to differ significantly between quartiles of stature using ANOVAanalysis. Conclusion: These results support the suggestion that short stature may be relevant to hyperglycemia, hypertension and hypercholesterolemia. Therefore, the measurement of metabolic risk markers could be useful in clinical screening for overweight and obese women of short stature.
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Abstract (Original Language): 
Amaç: K›sa boy baz› kardiyovasküler risk faktörleri ile iliflki göstermektedir. Bu çal›flma fazla kilolu ve fliflman kad› nlarda boy uzunlu¤u ile çeflitli kardiyovasküler risk faktörleri aras›ndaki iliflkiyi araflt›rmak amac›yla gerçeklefltirildi. Gereç ve yöntem: Beden kitle indeksi 25-67 kg/m2 aras›nda de¤iflen 3665 fazla kilolu ve fliflman kad›nda boy ile serum glukoz, ürik asit, total ve HDL-kolesterol, trigliserit, insülin, HOMA (homeostasis model assessment), sistolik ve diyastolik damar bas›nc› aras›ndaki iliflki, korelasyon analizi ve boy uzunlu¤una göre ayr›lm›fl dört grupta ANOVA, efllenmemifl seri t-testi ve ki-kare testi ile araflt›r›ld›. Bulgular: Olgularda boy uzunlu¤u ile a¤›rl›k ve HDL kolesterol aras›nda anlaml› pozitif, boy uzunlu¤u ile yafl, beden kitle indeksi, glukoz, kolesterol, trigliserit, maksimum ve minimum damar bas›nc› ve bel-kalça oran› aras›nda anlaml› negatif iliflkiler bulundu. Boy ile ürik asit, insülin ve HOMA aras›nda anlaml› bir iliflki saptanmad›. Boy uzunlu¤una göre dört gruba ayr›lan olgularda ANOVA ile yafl, a¤›rl›k, beden kitle indeksi, glukoz, maksimum ve minimum damar bas›nc›, kolesterol, trigliserit ve bel kalça oran› aç›s›ndan gruplararas› anlaml› farklar bulundu. Vakalarda çeyrek gruplar aras›nda diabetes mellitus, hipertansiyon, hiperkolesterolemi ve abdominal fliflmanl›k varl›- ¤› bak›m›ndan anlaml› farkl›l›k bulundu. Aksine hipertrigliseridemi ve HDL-kolesterol düflüklü¤ü varl›¤› aç›s›ndan anlaml› bir fark saptanmad›. Sonuç: Bulgular›m›z, fazla kilolu ve fliflman kad›nlarda k›sa boyun hiperglisemi, hipertansiyon ve hiperkolesterolemi gibi tablolar birlikte olabilece¤ini desteklemektedir. Bu nedenle k›sa boylu ve fazla kilolu veya fliflman olan kad›nlar kardiyovasküler risk varl›¤› bak›m›ndan daha yak›ndan izlenmelidir.
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