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İNVAZİV MANTAR HASTALIKLARININ MİKOLOJİK TANISI

MYCOLOGICAL DIAGNOSIS OF INVASIVE MYCOSES

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Abstract (2. Language): 
Nowadays, invasive mycoses still continue to be the most important cause of morbidity and mortality particularly in immunosuppressed patients. Due to quick progress and difficulty in defining the infection, definite diagnosis is possible mostly during autopsy application. It has strikingly been shown that fast and reliable laboratory tests have great importance for early diagnosis of the infection since the rate of mortality reached to 40-70%. In this article, the fungi that are or could be responsible agents of invasive mycoses and their laboratory diagnostic tests are reviewed.
Abstract (Original Language): 
‹nvaziv mantar infeksiyonlar›, günümüzde özellikle riskli konumdaki immünosupressif hastalar aç›s›ndan önemli bir morbidite ve mortalite nedeni olmaya devam etmektedir. ‹nfeksiyonun çok h›zl› ilerlemesi ve tan›mlanmas›ndaki güçlükler sonucunda kesin tan› ço¤unlukla otopsi esnas›nda konur. Mortalitenin % 40-70’lere ulaflm›fl olmas› erken ve gerçekçi laboratuvar testlerine olan gereksinimin ne denli önemli oldu¤unu çarp›c› bir biçimde vurgulamaktad›r. Bu derlemede invaziv mikoz etkeni olan/olabilen mantarlar ve laboratuvar tan› testlerinden söz edilmifltir.

REFERENCES

References: 

1. Bialek R, Konrad F, Kern J, Aepinus C, Cecenas L, Gonzales GM
Just-Nubling G, Willinger B,Presterl E, Lass-Florl C,Rickerts V.
PCR based identification and discrimination of agents of mucormycosis
and aspergillosis in paraffin wax embedded tissue. J
Clin Pathol 2005; 58:1180-1184.
2. Bradsher RW. Blastomycoses. In: Dismukes WE, Pappas PG, Sobel
JD (eds). Clinical mycology. Oxford University Press. New-
York, USA, 2003; pp 299-310.
3. de Repentigny L, Serological techniques for diagnosis of fungal infection.
Eur J Clin Microbiol Infect Dis 1989; 8:361-375.
4. de Valk HA, Meis JF, Curfs IM, Muehlethaler K, Mouton JW,
Klassen CH. Use of a novel panel of nine short tandem repeats for
exact and high-resolution fingerprinting of Aspergillus fumigatus
isolates. J Clin Microbiol 2005; 43:4112-4120.
5. Dupont P, Pappas PG, Dismukes WE. Fungal infections among patients
with AIDS. In: Dismukes WE, Pappas PG, Sobel JD (eds).
Clinical mycology. Oxford University Press. NewYork, 2003; pp
188-205.
6. Frank U, Malkotis D, Mlangeni D, Daschner FD. Controlled clinical
comparison of three commercial blood culture systems. Eur J
Clin Microbiol Infect Dis 1999; 18:248-255.
7. Gomez BL, Figuero JL, Hamilton AJ, Ortiz BL, Robledo MA,
Restrepo AHay RJ. Development of a novel antigen test for histoplasmosis
J Clin Microbiol 1997; 35:2618-2622.
8. Guinvarc’h A, Guilbert L ,Marmorat-Khuong A, Lavarde V, Chevalier
P, Guillemain R, Berrebi A. Disseminated Fusarium solani
infection with endocarditis in a lung transplant recipient. Mycoses
1998; 41: 59-61.
9. Kern ME. Medical mycology a self-instructional text, FA Davis
Co. Philadelphia, USA, 3nd ed; 1988.
10. Kwon-Chung KJ, Bennett JE. Medical mycology, Lea&Febiger.
Philadelphia, USA, 1992.
11. Larone DM. Medical important fungi,a quide to identification,
ASM Press. Washington D.C, USA, 4nd ed; 2002.
12. Linke MJ, Rebholz S, Collins M, Tanaka R, Cushion MT. Noninvasive
method for monitoring Pneumocystis carinii pneumonia.
Emerg Infect Dis 2003; 9:1613-1616.
13. Merz WF, Roberts GD. Algorithms for detection and identification
of fungi. In: Murray PR, Baron EJ, Jorgensen JM, Pfaller MA
(eds). Manual of Clinical Microbiology. ASM Press. Washington,
USA, 8nd., 2003; pp 299-310.
14. Ng L, Virani NA, Chaisson RE, Yajko DM, Sphar HT, Cabrian K,
Rollins N, Charache P, Krieger M, Hadley WK. Rapid detection of
Pneumocystis carinii using a direct fluorescent monoclonal antibody
stain. J Clin Microbiol 1990;28:2228-2233.
15. O’Shaughnessy EM, Shea YM, Witebsky FG. Laboratory diagnosis
of invasive mycoses. Infect Dis Clin N Am 2003; 17:135-158.
16. Peterson DL. New clinical presentations of invasive aspergillosis in
non-conventional hosts. Clin Microbiol Infect 2004; 10:24-30.
17. Pfaller MA, Diekema DJ. Twelve years of fluconazole in clinical
practice: global trends in species distribution and fluconazole susceptibility
of bloodstream isolates of Candida. Clin Microbiol Infect
2004; 10:11-23.
18. Richardson MD, Warnock DW. Fungal infection, diagnosis and
management, Blackwell Pub Ltd. Massachusetts, USA, 3nd ed;
2003.
19. Sandhu GS, Kline BC, Stockman L, Roberts GD.Molecular probes
for diagnosis of fungal infections. J Clin Microbiol 1995; 33:2913-
2919.
20. Sar›bafl Z, Ar›kan S(çevirenler).Patojen mantarlar›n moleküler yöntemlerle
saptanmas›. ‹çinde: Tekeli A, Ustaçelebi fi(çeviri editörleri).
Moleküler mikrobiyoloji, tan› prensipleri ve uygulamalar.”Persing
DH, Tenover FC, Versalovic J, Tang YW, Unger ER, Relman
DA, White TJ (eds): Molecular microbiology, diagnostic principles
and practice” kitab›ndan. Palme yay›nc›l›k. Ankara, 2006; 551-559.
21. Stockman L, Clark KA, Hunt JM, Roberts GD. Evaluation of commercially
available acridinium ester-labeled chemiluminescent
DNAprobes for culture identification of Blastomyces dermatitidis,
Coccidioides immitis, Cryptococcus neoformans and Histoplasma
capsulatum. J Clin Microbiol 1993; 31:845-850.
22 Stringer JR, Beard CB, Miller RF, Wakefield E. Anew name (Pneumocystis
Jiroveci) for Pneumocystis from humans. Emerg Infect
Dis 2002; 8:891-896.
23. Sutton DA. Specimen collection, transport and proccessing: Mycology
In: Murray PR, Baron EJ, Jorgensen JH, Pfaller MA (eds).
Manual of clinical microbiology. ASM Press Washington, USA,
8nd ed., 2003; pp 1659-1667.
24. Tanner DC, Weinstein MP, Fedorciw B, Joho KL, Thorpe JJ, Reller
L. Comparison of commercial kits for detection of cryptococcal
antigen. J Clin Microbiol 1994; 32:1680-1684.
25. Tavanti A, Davidson AD,Johnson EM, Maiden MC, Shaw DJ,
Gow NA, Odds FC. Multilocus sequencetyping for differentiation
of strains of Candida tropicalis. J Clin Microbiol 2005; 43:5593-
5600.
26. Vanbreuseghem R, Vroey CH De, Takashio M. Practical quide to
medical and veterinery mycology, Masson Pub. NewYork, USA,
2nd ed., 1978.
27. Walsh TJ, Fancesconi A, Kasai M, Chanock SJ. PCR and singlestrand
conformational polymorphism for recognition of medically
important opportunistic fungi. J Clin Microbiol 1995; 33:3216-
3220.
28. Walsh TJ, Groll A, Hiemenz J, Fleming R, Roilides E, Anaissie E.
Infections due to emerging and uncommon medically important
fungal pathogens. Clin Microbiol Infect 2004; 10: 48-66.
29. Welty FK, McLeod GX, Ezratty C, Healy RW, Karchmer E. Pseudallescheria
boydii endocarditis of the pulmonic valve in a liver
transplant recipient. Clin Infect Dis 1992; 15:858-860.
30. Wheat LJ. Rapid diagnosis of invasive aspergillosis by antigen detection.
Transpl Infect Dis 2003; 5:158-166.
31. Wheat LJ. Current diagnosis of histoplasmosis. Trends Microbiol
2003; 11:488-494.
32. Yeo SF, Wong B. Current status of nonculture methods for diagnosis
of invasive fungal infections. Clin Microbiol Rev 2002; 15:465-
484.

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