You are here

KRİPTOJENİK KARACİĞER SİROZU - PERNİSİYÖZ ANEMİ BİRLİKTELİĞİ

PERNICIOUS ANEMIAASSOCIATED WITH CRYPTOGENIC CIRRHOSIS

Journal Name:

Publication Year:

Abstract (2. Language): 
Cytopenia may occur in cirrhosis due to hypersplenism. However severe cytopenia is rare in cirrhosis. In this situation, together with diseases of bone marrow infiltration pernicious anemia with pancytopenia should also be considered in differential diagnosis. In literature, association of pernicious anemia and chronic liver disease was reported as a case presentation. In this paper a case with severe pancytopenia which has been proved as cryptogenic liver cirrhosis is presented.
Abstract (Original Language): 
Karaci¤er sirozunda hipersplenizme ba¤l› olarak de¤iflik derecede sitopeniler görülebilir. Ancak a¤›r pansitopeni mutad de¤ildir. Bu durumda kemik ili¤ini infiltre eden hastal›klar ile birlikte, pansitopeniyle seyreden pernisyöz anemi de ay›r›c› tan›da akla gelmelidir. Literatürde kronik karaci¤er hastal›¤› (primer biliyer siroz, otoimmün hepatit vb) ile pernisyöz anemi birlikteli¤i, vaka sunumlar› fleklinde bildirilmifltir. Bu yaz›da, a¤›r pansitopeni ile baflvuran ve kriptojenik siroz oldu¤u saptanan pernisyöz anemili bir vaka sunulmufltur
107-110

REFERENCES

References: 

1. Aitelli C, Wasson L, Page R. Pernicious anemia: presentations
mimicking acute leukemia.South. Med J 2004; 97:295-297.
2. Alderuccio F, Sentry J.W., Marshall A.C., Biondo M, Toh B.H.
Animal models of human disease: experimental autoimmune
gastritis. A model for autoimmune gastritis and pernicious anemia,
Clin Immunol 2002; 102:48-58.
3. Alvarez F, Berg PA, Bianchi FB, Bianchi L, Burroughs AK,
Cancado EL, Chapman RW, Cooksley WG, Czaja AJ, Desmet
VJ, Donaldson PT, Eddleston AL, Fainboim L, Heathcote
J, Homberg JC, Hoofnagle JH, Kakumu S, Krawitt EL,
Mackay IR, MacSween RN, Maddrey WC, Manns MP,
McFarlane IG, Meyer zum Büschenfelde KH, Zeniya M, International
Autoimmune Hepatitis Group Report: Review
criteria for diagnosis of autoimmune hepatitis. J Hepatol
1999; 31: 929-938.
4. Andres E, Loukili NH, Ben Abdelghani M, Noel E. Pernicious
anemia associated with interferon-alpha therapy and chronic hepatitis
C infection. J Clin Gastroenterol 2004 ; 38:382-385.
5. Angela GC, Fazio A case of pernicious anemia associated with
hepatic cirrhosis M. Gazz Med Ital 1953; 112:68-71.
Cryptogenic cirrhosis
‹stanbul T›p Fakültesi Dergisi Cilt / Volume: 70 • Say› / Number: 4 • Y›l/Year: 2007
- 109 -
6. Aoyama H, Sakugawa H, Nakasone H, Nakayoshi T, Kinjo A,
Tamayose M, Higa H, Uema A, Chinen T, Tomiyama R, Uchima
N, Kugai Y, Kinjo F, Saito A and Kinjo M. A rare association
of primary biliary cirrhosis and pernicious anemia. J Gastroenterol
2002; 37: 560-563.
7. Attout H, Guez S, Series C. Association of hereditary hemochromatosis
and pernicious anaemia Rev. Med. Interne 2004 ;
25:759-761.
8. Bergwitz C, Brabant G, Trautwein C, Manns MP. Apatient with
autoimmune hepatitis type I, Addison's disease, atrophic thyroiditis,
atrophic gastritis, exocrine pancreatic insufficiency, and
heterozygous alpha1-antitrypsin deficiency. Am J Gastroenterol
2002; 97:1050-1052.
9. Deanne LV, Greenwoda John W. Sentrya, Murine experimental
autoimmune gastritis models refractive to development of intrinsic
factor autoantibodies, cobalamin deficiency and pernicious
anemia. Clin Immunol 2007; 122, 41-52.
10. Dohmen K. Primary biliary cirrhosis and pernicious anemia
Gastroenterology and Hepatology 2001; 16: 1316-1318.
11. Field J, Biondo MA, Murphy K, Alderuccio F, Toh BH. Experimental
autoimmune gastritis: mouse models of human organspecific
autoimmune disease, Int. Rev. Immunol 2005; 24: 93-
110.
12. Kazufimi D, Hirohisa S, Yuichi M, Fumio Y, Koji I, Hiromi I.
Atrophic Corpus Gastritis and Helicobacter Pylori Infection in
Primary Biliary Cirrhosis. Digestive Diseases and Sciences,
2002; 47: 1, 162–169.
13. Loukili NH, Noel E, Blaison G, Goichot B, Kaltenbach G, Rondeau
M, Andres E. [Update of pernicious anemia. Aretrospective
study of 49 cases] Rev. Med. Interne 2004 ; 25:556-561.
14. Olmer J, Moutaffian A case of Biermer's anemia with liver cirrhosis
(development followed for 14 years, death due to hepatocarcinoma)]
JJ.Mars Med 1969; 106; 345-348.
15. Scalabrino G, Peracchi M. New insights into the pathophysiology
of cobalamin deficiency Trends in Molecular Medicine
2006; 12:6, 247-254.
16. Takahashi T, Honma T, Ishizuka K, Fuse I, Asakura H. A female
with asymptomatic primary biliary cirrhosis associated with
pernicious anemia. J. Gastroenterol Hepatol 2001; 1: 6, 1420-
1424.

Thank you for copying data from http://www.arastirmax.com