ADRENALADENOMAAND FALSE POSITIVE HIGH URINE CATECHOLAMINES IN ACROMEGALY: CASE REPORT
Journal Name:
- İstanbul Tıp Fakültesi Dergisi
Key Words:
Keywords (Original Language):
Author Name | University of Author | Faculty of Author |
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Abstract (2. Language):
Acromegaly is a known risk factor for ischemic heart disease. An adrenal adenoma along with increased urine catecholamine
levels is highly indicative of pheochromocytoma. However, ischemic heart disease can cause increment
in the urine catecholamines. Herein, we present a case having classic features of acromegaly and ischemic heart
disease. On his thorax computed tomography scan performed for paracardiac opacity on X-ray, there was an adrenal
adenoma and his urine catecholamine levels were high. After he underwent coronary by-pass grafting operation,
his urine catecholamine levels returned to normal. If clinical probability of pheochromocytoma is low in the
setting of increased urine catecholamines, other sympathic activation causes like ischemic heart disease, should be
considered and excluded before pheochromocytoma is diagnosed.
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Abstract (Original Language):
Akromegali, iskemik kalp hastal›¤› için bilinen bir risk faktörüdür. Adrenal adenom ile birlikte idrar katekolaminlerinde
art›fl olmas› durumunda feokromositoma ihtimali oldukça yüksektir. Bununla birlikte, iskemik kalp hastal›-
¤›na ba¤l› olarak da idrar katekolaminlerinde art›fl ortaya ç›kabilir. Yaz›m›zda, akromegalinin klasik özelliklerini bar›
nd›ran ve iskemik kalp hastal›¤› olan bir olgu sunmaktay›z. Olgumuzda posteroanterior akci¤er grafisinde saptanan
parakardiyak opasitenin incelenmesi için çekilen toraks bilgisayarl› tomografisinde (BT) bir adrenal adenom
tespit edilmifl ve idrar katekolamin seviyeleri yüksek bulunmufltur. Koroner arter by-pass greft operasyonu sonras›
nda idrar katekolamin seviyeleri normale dönmüfltür. ‹drar katekolaminleri yüksek bulundu¤unda, klinik olarak
feokromositoma ihtimali düflük ise, iskemik kalp hastal›¤› gibi sempatik aktivasyonun bulundu¤u durumlar akla getirilmeli
ve feokromositoma tan›s› konulmadan önce bu durumlar d›fllanmal›d›r.
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