You are here

Home » Content

YETİŞKİN ASTIM HASTALARINDA YAŞAM KALİTESİ VE YAŞAM KALİTESİNİ ETKİLEYEN FAKTÖRLERİN TANILANMASI

ASSESSMENT OF FACTORS AFFECTING QUALITY OF LIFE AND QUALITY OF LIFE IN ADULTASTHMATIC OUTPATIENTS

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2008

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
ABSTRACT Objective: The purpose of this study was to determine the quality of life of adult asthma patients compared to a healthy control group, and to evaluate the relationships between demographics, asthma-related variables, psychological status and health-related quality of life. Material and method: Those patients who were on routine follow-up at the outpatient Department of Chest Diseases between January 1 – May 30, 2005, literate, with no psychotic symptom or mental retardation, which had given informed consent for the study, were included in to the study (n=176). The Semi-structured Interview Form, the Revised Brief Patient Health Questionnaire (Brief PHQ-r), and the short version of the Health-related Quality of Life Scale (SF-36) were administered. 100 healthy adults from the general population matched sociodemoghraphically with asthma group formed the control group. Results: The mean age was 46.27 ± 11.46 years, women were 77.3%. The mean duration of the disease was 13.03±10.50 years. According to Global Initiative for Asthma (GINA) guidelines 47.2% were moderate persistent. The mean value of % predicted FEV1 was 86.62 ± 20.16. 29% of the cases defined psychiatric diagnosis according to Brief PHQ-r. The sub-domains on the SF-36 measurements of the asthma patients were significantly lower than those of the control subjects (p<0.05). Psychiatric diagnosis was found to decrease both physical and mental health dimensions of quality of life (p<0.001). Conclusion: Although physical parameters related to illness affected only the physical dimension, in patients with psychiatric morbidity, quality of life was significantly affected in all sub-dimensions.
Bookmark/Search this post with
Abstract (Original Language): 
Amaç: Bu çal›flman›n amac› yetiflkin ast›m hastalar›n›n yaflam kalitesini sa¤l›kl› kontrol grup ile karfl›laflt›rarak tan› mlamak ve hastalar›n yaflam kalitesi ile demografik, ast›mla ilgili de¤iflkenler, psikolojik durum aras›ndaki iliflkiyi de¤erlendirmektir. Gereç ve yöntem: Gö¤üs hastal›klar› anabilim dal› poliklini¤inde bir y›ld›r takipli olan hastalardan 1 Nisan-30 May› s 2005 tarihlerinde baflvuran, okur yazar olan, psikotik belirtileri veya mental retardasyon saptanmayan, çal›flmaya kat›lmay› kabul eden hastalar çal›flmaya al›nd› (n=176). Hastalara yar› yap›land›r›lm›fl görüflme formu, psikiyatrik tan›lama için standart tan› formu olan KISA (K›sa Sa¤l›k Anketi/Brief Patient Health Questionnaire-Brief PHQ), sa¤l›k alan›nda yaflam kalitesini de¤erlendirmek için SF-36 uyguland›. Kontrol grup, ast›ml› grupla sosyodemografik özellikleri efllefltirilmifl genel populasyondan seçilmifl 100 sa¤l›kl› yetiflkin ile oluflturulmufltur. Bulgular: Hastalar›n yafl ortalamas› 46,27 ± 11,46 y›l idi, %77,3’ü kad›nd›. Hastal›k süresi ortalama 13,03 ± 8,84 y›l idi. GINA (The Global Initiative for Asthma)’ya göre hastal›k evresi %47,2’si orta persistan düzeydeydi. Hastalar› n ortalama FEV1 yüzde de¤eri 86,62 ± 20,16 L idi. KISA’ya göre psikiyatrik tan› oran› %29 bulundu. Ast›m hastalar› n›n SF-36 yaflam kalitesinin tüm alt boyutlar›nda puanlar› kontrol grubundan düflük bulundu (p<0,05). Psikiyatrik bir tan›n›n varl›¤› hem fiziksel, hem mental sa¤l›k boyutunda yaflam kalitesini düflürdü¤ü saptand› (p<0,001). Sonuç: Hastal›kla ilgili fiziksel parametreler yaflam kalitesinin yaln›zca fiziksel boyutunu etkiledi¤i saptan›rken, psikiyatrik tan› konulan hastalarda ise tüm alt boyutlarda yaflam kalitesinin anlaml› düzeyde etkilendi¤i bulundu.
FULL TEXT (PDF): 
PDF icon arastirmax-yetiskin-astim-hastalarinda-yasam-kalitesi-yasam-kalitesini-etkileyen-faktorlerin-tanilanmasi.pdf
  • 4
109-115
  • English

REFERENCES

References: 

1- Abramson MJ, Bailey MJ, Couper FJ, Driver JS, Drummer OH,
Forbes AB. Are asthma medications and management related to
deaths from asthma? Am J Respir Crit Care Med 2001;163:12-
18.
2- American Psychiatric Association. Diagnostic and Statistical
Manual of Mental Disorders, 4th edn. American Psychiatric Association,
Washington, DC, 1994.
3- Apter AJ, Reisine ST, Affleck G, Barrows E, ZuWallack RL.
The influence of demographic and socioeconomic factors on health-
related quality of life in asthma. J Allergy Clin Immunol
1999;103:72-78.
4- Bonala SB, Pina D, Silverman BA, Amara S, Bassett CW,
Schneider AT. Asthma severity, psychiatric morbidity, and quality
of life: correlation with inhaled corticosteroid dose. J Asthma
2003;40:691–699.
5- Bousquet J, Knani J, Dhivert H, Richard A, Chicoye A, Ware JE
& Michel FB. Quality of life in asthma, I:Internal consistency
and validity of the SF-36 questionnaire. Am J Respir Crit Care
Med 1994;149:371–375.
6- CDC, National Center for Health Statistics. Asthma prevalence,
health care use and mortality, 2000–2001. Available at
http://www.cdc.gov/nchs/products/pubs/pubd/hestats/asthma/
asthma.htm.
7- Corapc›oglu A, Uzuner Ozer G. Adaptation of revised Brief
PHQ (Brief-PHQ-r) for diagnosis of depression, panic disorder
and somatoform disorder in primary healthcare settings. Int J
Psychiatr Clin Prac 2004;8:11-18.
8- Ekici A, Ekici M, Kara T, Keles H, Kocyigit P. Negative mood
and quality of life in patients with asthma. Quality of Life Research
2006;15:49–56.
9- Erickson SR, Christian RD, Kirking DM, Halman LJ. Relationship
between patient and disease characteristics, and health-related
quality of life in adults with asthma. Respiratory Medicine
2002;96:450-460.
10- Feldman JM, Lehrer PM, Borson S, Hallerstrand TS, Siddique
MI. Health care use and quality of life among patient with asthma
and panic disorder. J Asthma 2005;42:179–184.
11- Gaga M, Papageorgiou N, Zervas E, Gioulekas D, Konstatopoulos
S. Control of asthma under specialist care: is it achieved?
Chest 2005;128:78-84.
12- Global Initiative for Asthma. Global strategy for asthma management
and prevention NHLBI/ WHO workshop report. National
Heart, Lung and Blood Institute Publication Number 02-
3659, 1995; pp139-168.
13- Goldney RD, Ruffin R, Fisher LJ, Wilson DH. Asthma symptoms
associated with depression and lower quality of life: a population
survey. Med J Aust 2003;178:437–441.
14- Guyatt GH, Feeny DH, Patrick DL. Measuring health-related
quality of life. Ann Intern Med 1993;118:622-629.
15- Hazell M, Frank T, Frank P. Health related quality of life in individuals
with asthma related symptoms. Respiratory Medicine
2003;97:1211–1218.
16- Henkel V, Mergl R, Kohnen R, Maier W, Moller HJ, Hegerl U.
Identifying depression in primary care: a comparison of different
methods in a prospective cohort study. British Medical Journal
2003;326:200-201.
17- Hopman WM, Towheed T, Anastassiades T, Tenenhouse A, Poliquin
S, Berger C, Joseph L, Brown JP, Murray TM, Adachi JD,
Hanley DA, Papadimitropoulos E, The Canadian Mulitcentre
Osteoporosis Study Research Group. Canadian normative data
for the SF-36 Health Survey. Can Med Assoc J
2000;163:265–271.
18- Juniper EF, Guyatt GH, Ferrie PJ, Griffith LE. Measuring quality
of life in asthma. Am Rev Respir Dis 1993;147:832-838.
19- Juniper EF, Guyatt GH, Epstein RS, Ferrie PJ, Jaeschke R, Hiller
TK. Evaluation of impairment of health related quality of life
in asthma: Development of a questionnaire for use in clinical
trials. Thorax 1992;47:76–83.
20- Juniper EF. Assessing health-related quality of life in asthma.
Can Respir J 1997;3:17–20.
21- Kalyoncu AF, Karakoca Y, Demir AU, Alpar R, Shehu V, Coplu
L, Sahin AA, Baris YI. Prevalence of asthma and allergic diseases
in Turkish university students in Ankara. Allergol Immunopathol
1996;24:152-157.
22- Kalyoncu F. Kalyoncu F. ‹ç, Do¤u ve Güneydo¤u Anadolu Bölgesi'nde
ast›m ve di¤er allerjik hastal›klar›n epidemiyolojisi.
Alerji ve ‹mmünoloji Bülteni 1998;10; 23-26.
23- Klinnert MD. Evaluating the effects of stress on asthma: Aparadoxical
challenge. Eur Respir J 2003;22:574–575.
24- Kocyi¤it H, Aydemir O, Fiflek G, Ölmez N, Memifl A. K›sa
form-36'n›n Türkçe versiyonunun güvenilirli¤i ve geçerlili¤i.
‹laç ve Tedavi Dergisi 1999; 12: 102-6.
25- Küçükusta AR. Epidemiyoloji. In: Gemicio¤lu B; ed. Tan›mdan
tedaviye ast›m. ‹stanbul: Turgut Yay›nc›l›k, 1. bas›m, 2005; pp 5-
26.
26- Lavoie KL, Cartier A, Labrecque M, Bacon SL, Lemiere C, Malo
JL, Lacoste G, Barone S, Verrier P, Ditto B. Are psychiatric disorders
associated with worse asthma control and quality of life
in asthma patients? Respir Med 2005;99:1249–1257.
27- Lavoie KL, Bacon SL, Barone S, Cartier A, Ditto B, Labrecque
M. What is worse for asthma control and quality of life: depressive
disorders, anxiety disorders, or both? Chest
2006;130(4):1039-47.
28- Lipton MW, McConnachie A, McSharry C, Hart CL, Smith GD,
Gillis CR, Watt GCM. Intergenerational twenty-year trends in
the prevalence of asthma and hay fever in adults: the Midspan
family study survey of parents and offspring. BMJ
2000;321:88–92.
29- Löwe B, Graefe K, Kroenke K, Zipfel S, Quenter A, Wild B, Fiehn
C, Herzog W. Predictors of psychiatric comorbidity in medical
outpatients. Psychosomatic Medicine 2003;65:764-770.
30- Mancuso CA, Peterson MG, Charlson ME. Effects of depressive
symptoms on health-related quality of life in asthma patients.
Gen Intern Med J 2000;15:301–310.
31- Manocchia M, Keller S, Ware JE. Sleep problems, health-related
quality of life, work functioning and health care utilization
among the chronically ill. Qual Life Res 2001;10:331-345.
32- Moy ML, Israel E, Weiss ST, Juniper EF, Dube L, Drazen JM,
NHBLI. Asthma Clinical Research Network. Clinical predictors
Quality of Life in Adult Asthmatics
‹stanbul T›p Fakültesi Dergisi Cilt / Volume: 71 • Say› / Number: 4 • Y›l/Year: 2008
- 114 -
of health-related quality of life depend on asthma severity. Am J
Respir Crit Care Med 2001;163:924– 929.
33- O¤uztürk O, Ekici A, Kara M, Ekici M, Arslan M, Iteginl, A, Kara
T, Kurtipek E. Psychological status and quality of life in elderly
patients with asthma. Psychosomatics 2005;46:41-46.
34- Osborne ML, Vollmer WM, Linton KLP, Buist AS. Characteristics
of patients with asthma within a large HMO: a comparison
by age and gender. Am J Respir Crit Care Med
1998;157:123–128.
35- Ozkan M, Kocaman N, Ozkan S, Erden S, Demirel S, Dilmener
M. Mood, panic and somatoform disorders in general Turkish
outpatient clinic. Primary Care and Community Psychiatry
2006;11:1-5.
36- Plaza V, Serra-Batlles J, Ferrer M, Morejon E. Quality of life and
economic features in elderly asthmatics. Respiration
2000;67:65-70.
37- Rabe KF, Vermeire PA, Soriano JB, Maier WC. Clinical management
of asthma in 1999: The Asthma Insights and Reality in
Europe (AIRE) study. Eur Respir J 2001;18:248.
38- Schmier JK, Chan KS, Leidy NK. The impact of asthma on health
related quality of life. J. Asthma 1988;35:585-597.
39- Sekerel BE, Gemicioglu B. Soriano JB. Asthma insights and reality
in Turkey (AIRET) study. Respir Med 2006; 100:1850-4.
40- Spitzer RL, Kroenke K,Williams JB. Validation and utility of a
self-report version of PRIME-MD: the PHQ primary care study.
Primary Care Evaluation of Mental Disorders. Patient Health
Questionnaire. JAMA 1999;10, 282:1737-1744.
41- Spitzer RL, Williams JB, Kroenke K, Kroenke K, Linzer M,
deGruy FV, Hahn SR, Brody D, Johnson JG. Utility of a new
procedure for diagnosing mental disorders in primary care The
PRIME-MD 1000 Study. JAMA 1994;272:1749-1756.
42- Strine TW, Ford ES, Balluz L, Chapman DP, Mokdad AH. Risk
behaviors and health-related quality of life among adults with
asthma: the role of mental health status. Chest
2004;126:1849–1854.
43- Testa MA, Simonson DC. Assessment of quality-of-life outcomes.
N Engl J Med 1996;334:835-840.
44- Tovt-Korshynska MI, Dew MA, Chopey IV, Spivak MY, Lemko
IS. Gender differences in psychological distress in adults with
asthma. J Psychosomatic Res 2001;51:629–637.
45-Ware JE, Snow KK, Kosinkio M, Gandek B. SF-36 Health Survey
Manual and Interpretation Guide. The Health Institute; New
England Medical Center, Boston, NY, 1993.
46-Weiss KB, Gergen PS, Hodgson TA. An economic valuation of
asthma in the United States. N Eng J Med 1992; 326: 862-66.
47-Weiss KB, Buist SA, Sullivan SD. Asthma’s Impact on Society.
Marcal Dekker, New York, 2000.
48-Woolcock AJ. Worldwide differences in asthma prevalence and
mortality. Chest 1990;90:405-455.
49-World Health Organization: Bronchial asthma.
http://www.who.int/mediacentre/factsheets/fs206/en/print.html
(revised January 2000).
50- Young SY, Gunzenhauser JD, Malone KE, McTiernan A. Body
mass index and asthma in the military population of the northwestern
United States. Arch Intern Med 2001;161:1605-1611.

Thank you for copying data from http://www.arastirmax.com