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GASTROÖZOFAJEAL REFLÜ HASTALIĞI: LARENKS KANSERİNDE ETKEN BİR FAKTÖR MÜDÜR?

GASTROESOPHAGEAL REFLUX DISEASE: IS IT A CAUSATIVE FACTOR IN LARYNGEAL CANCER?

Journal Name:

  • İstanbul Tıp Fakültesi Dergisi

Publication Year:

  • 2011

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Gastroesophageal reflux disease is an extremely common disorder and has seen an explosion in interest from both scientific communities and the general public, resulting in an abundance of misleading and even conflicting information. Previously published reports suggested that gastroesophageal reflux disease is associated with laryngeal cancer, but today there are many publications which do not support this argument. However, gastroesophageal reflux disease may lead to esophageal and upper respiratory epithelial destruction causing Barrett‟s esophagus and esophageal adenocarcinoma, laryngitis, pharyngitis, eustachian tube abnormalities, chronic sinusitis, pneumonia and asthma. In this review, the link between the gastroesophageal reflux disease and laryngeal cancer is investigated.
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Abstract (Original Language): 
Gastroözofajeal reflü hastalığı oldukça sık karĢılaĢılan bir rahatsızlık olması nedeniyle hem bilimsel camiada hem de halk arasında giderek artan bir ilgiye neden olmaktadır. Ancak bu ilgi aynı zamanda oldukça fazla miktarda yanlıĢ hatta çeliĢkili bilgilerin ortaya çıkmasına neden olmuĢtur. BaĢlangıçtaki yayınlar gastroözofajeal reflü hastalığını larenks kanseri ile iliĢkilendirirken, son dönemlerde yapılan çalıĢmalar bu bağlantıyı desteklememektedir. Ancak gastroözofajeal reflü hastalığı özefagus ve üst solunum yolu epitelinde destrüksüyona yol açarak Barrett özefajitine, özefagus adenokarsinomuna, larenjit, farenjit, östaki tüpü fonksiyon bozukluklarına, kronik sinüzite, pnömoni ve astıma neden olabilir. Bu derlemede gastroözofajeal reflü hastalığı ile larengeal kanser arasındaki iliĢki araĢtırılmıĢtır.
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  • 3
55-58
  • English

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