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HİDROFİLİK KUMLANMIŞ-ASİTLENMİŞ YÜZEYLİ İMPLANTLARIN HİSTOLOJİK VE HİSTOMORFOMETRİK İNCELEMESİ: KOYUN TİBİASINDA DENEYSEL ÇALIŞMA

HISTOLOGIC AND HISTOMORPHOMETRIC EVALUATION OF A HYDROPHILIC BLASTED AND ACID-ETCHED IMPLANT: AN EXPERIMENTAL STUDY IN SHEEP TIBIA

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Abstract (2. Language): 
The aim of this study was to evaluate the early term osseointegration period of a modified sand-blasted and acid-etched (modSLA) implant in an experimental animal model. A total of 30 implants were placed to the tibiae of 3 sheep and insertion torque value (ITV) and resonance frequency analysis (RFA) measurements were performed. RFA measurement was repeated on 3 and 6 weeks healed implants which the animals were also sacrificed for histomorphometric analysis. Bone-to-implant contact was assessed on non-decalcified sections. Six weeks healed implants were also subjected to reverse torque test (RTT). Result s were analyzed by analysis of variance (ANOVA) and Pearson correlation tests. All implants reached to strong primary stability with a mean 35.47±2.85 N/cm ITV and 71.60±2.87 RFA values for modSLA implants. After 3 weeks of healing, mean BIC% (80.64±13.89%) and RFA value (76.80±1.14) of modSLA implants were higher than of standard implants (64.39±21.2 BIC% and 74.20±4.76 RFA) and the differences were statistically significant. The differences were no more significant after 6 weeks of healing as confirmed by the RTT test (115.2±4.14 and 117.0±4.47 N/cm for standard and modSLA implants respectively, p=0.55). No correlations were found between any of the investigated parameters. Within the limits of this pilot study it can be concluded that modSLA implants achieves higher bone contact and stability at earlier time points compared to standard implants.
Abstract (Original Language): 
Bu çalışmanın amacı, standartkumlanmış-asitlenmiş implantlarla (SLA), modifıye yüzeye sahip implantların (modSLA) iyileşme dönemindeki osteointegrasyon özelliklerinin hayvanlar üzerinde deneysel olarak karşılaştırılmasıdır. Üç koyunun tibialannın metafasiyal bölgesine 30 implant yerleştirilmiş, rezonans frekans analizi (RFA) ve geri çevirme tork testi yapılmıştır. 3 ve 6. haftalarda RFA ölçümleri tekrar edilmiş ve aynı haftalarda non-dekalsifıye kesitler üzerinde histomorfometrik analizler yapılmıştır. İyileşmenin 6.haftasında implantlara geri çevirme tork testi uygulanmıştır. Sonuçlar varyans analizi (ANOVA) ve Pearson korelasyon testi kullanarak analiz edilmiştir. Tüm implantlar yüksek primer stabiliteye ulaşmıştır; yerleşim torku (ITV) değerleri ortalama 36.13±2.47 ve 35.47±2.85 N/cm olarak belirlenmiştir. SLA ve modSLA implantların RFA değerleri sırasıyla 72.27±3.17 ve 71.60±2.87 olarak bulunmuştur. İyileşmenin 3. haftasında, ortalama kemik implant kontakt yüzdesi (%80.64±13.89) ve RFA (76.80±1.14) değeri modSLA implantlarda SLA implantlardan daha yüksek bulunmuştur. Ancak iyileşmenin ö.haftasmdan geri çevirme tork testi değerleri açısından SLA (115.2±4.14) ve modSLA (117.0±4.47N/cm) implantlar arasında anlamlı bir fark bulunamamıştır(p=0.55). İncelenenparametreler arasında istatistiksel anlamlı korelasyon bulunamamıştır. Bu pilot çalışmamn verileri ışığında, modSLA implantlann SLA implantlara göre erken iyileşme döneminde daha yüksek kemik temasına ve stabiliteye sahip olduğu söylenebilir
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