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KAHRAMANMARAŞ YÖRESİNDE ABO VE Rh(D) GEN FREKANSLARININ İNCELENMESİ

INVESTIGATION OF ABO AND Rh(D) GENE FREQUENCIES IN KAHRAMANMARAŞ AREA

Journal Name:

  • Kahramanmaraş Sütçü İmam Üniversitesi Doğa Bilimleri Dergisi

Publication Year:

  • 2001

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, ABO and Rh(D) gene frequencies were determined based on blood samples collected from 1969 unrelated individuals of both sexes living in Kahramanmaraş area. The results of this study, were compared with those of obtained 30 years ago for the purpose of investigating whether there was any differences in the gene frequencies and also whether there was any divergence from Hardy-Weinberg equilibrium in the population. These 1969 individuals were those who applied to Blood Centre of Kahramanmaraş Puplic Hospital for the determination of their phenotype with respect to ABO and Rh(D) genes during the period January-July 2000. The obtained results were statistically evaluated. The calculated gene frequencies in Kahramanmaraş area were as follows: A= 0.2687±0.0070, B=0.1525±0.0057, O=0.5788±0.0078; Rh(D)=0.6743±0.0074, Rh(d)=0.3257±0.0074. The comparison of the results of this study with those of belong to 30 years ago showed that there was no statistically significant differences in the ABO and Rh(D) gene frequencies of Kahramanmaraş area.
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Abstract (Original Language): 
Bu çalışmada, Kahramanmaraş yöresinde yaşayan, aralarında akrabalık ilişkisi bulunmayan, her iki cinsiyette, 1969 kişiden oluşan bir populasyon örneğinde ABO ve Rh(D) kan gruplarının gen frekansları hesaplanmıştır. Elde edilen sonuçlar, 30 yıl öncesine ait ABO ve Rh(D) gen frekansları ile karşılaştırılarak, bu zaman diliminde gen frekanslarında değişiklik olup olmadığı ve populasyonun dengede kalıp kalmadığı araştırılmıştır. Ocak-Temmuz 2000 tarihleri arasında, Kahramanmaraş Devlet Hastanesi Kan Merkezi’ne değişik nedenlerle ABO ve Rh(D) fenotipini öğrenmek için gelen kişilere ait sonuçlar istatistiksel olarak değerlendirilmiştir. K.Maraş yöresi için gen frekansları; A=0.2687±0.0070, B=0.1525±0.0057, O=0.5788±0.0078; Rh(D)=0.6743±0.0074, Rh(d)=0.3257±0.0074 olarak hesaplanmıştır. 30 yıl öncesine ait gen frekansları ile yapılan karşılaştırma sonucunda, gen frekanslarında istatistiksel olarak anlamlı bir farklılık olmadığı görülmüştür.
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