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Meme karsinomalarında aksiller lenf nodlanndaki metastazların özellikleri ve mikrometastazlann belirlenmesinde seri kesitlerin etkinliği

Features of metastases in axillary İymph nodes from breast carcinomas and effecövenes of serial secöoning in detec-ü'on of micrometastases

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Abstract (2. Language): 
For the assesment of the suitable therapy and prognosis; some histopathologicai features especiaily determining axil-lary iymph nodes correctiy becomes so much important. Betvveen the years 1998 and 200 i at Selçuk University Meram Medical Faculty Pathoiogy Laboratory 777 axiiiary İymph nodes materials obtained from 47 modifıed mastec-tomy examined retrospectively for determining the micrometastasis that couldn't be found before. After serial sections in 2 of 19 cases micrometastasis were found. These İ 9 patient were said not to have metastasis before. The incidence of fınding micrometastasis decreased as the serial section counts increased. 7\s a result; serial section method is more effective than routine examinations for determining the micrometastasis and in the examinations using 20p section intervat and taking 6 sections is a recommendabie method.
Abstract (Original Language): 
Meme kanserinin prognozunun ve uygun tedavisinin tayininde bazı histopatolojik özellikler, özellikle de aksiller lenf nodu durumunun doğru bir şekilde tespit edilmesi önemli hale gelmiştir 1988-200 i yıllan arasında S. Ü. Meram Tıp Fakültesi Patoloji Laboratuarında 47 modifıye mastektomi materyalinden tespit edilen 777 aksiller lenf nodu retrospektif olarak daha önce belirlenemeyen mikrometastazlann belirlenmesi için incelendi. Uygulanan seri kesitler sonucu metas¬taz bulunmadığı rapor edilen 19 vakanın 2 /%! ij'sinde mîkrometastaz tespit edildi Mîkrometastaz bulma oranı 6. kesite kadar artmakta, sonraki kesitlerde azalmakta idi. Sonuç olarak seri kesit tekniğinin rutin incelemeye göre metas¬tazları tespit etmede daha etkili olduğu ortaya konuldu ve incelemelerde 20 pm kesit aralıklarında 6 kesit yapmanın tavsiye edilebilir bir yöntem olduğu kanısına varıldı.
99-103

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