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ORTA KULAK CERRAHİSİNDE POSTOPERATİF BULANTI-KUSMANIN ÖNLENMESİNDE ONDANSETRON VE HALOPERİDOL'ÜN ETKİLERİNİN KARŞILAŞTIRILMASI

Comparison of the effects of ondansetron and haloperidol on postoperative nausea and vomiting in middle ear surgery

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Aim: The aim of this study is to compare the prophylactic administration of ondansetron with halope-ridol to determine its effects in reducing postoperative nausea and vomiting after middle ear surgery. Material and Method: Forty patients scheduled for middle ear surgery under general anesthesia were randomly allocated in two groups to receive either haloperidol IV 2 mg (Group I) or ondanset-ron IV 4 mg (Group II) 5 minutes before induction of anesthesia. Standart general anesthesia was applied. During postoperative 24 hours nausea-vomiting was evaluated by using verbal descriptive scala. Results: The nausea-vomiting score was not statistically different between the groups (p>0.05). The incidence of nausea-vomiting and the need for rescue antiemetics were not statistically significant (p>0.05). There was no difference of side effects between the groups (p>0.05). Conclusion: It was concluded that haloperidol 2 mg is as effective as ondansetron 4 mg for the prevention of pos¬toperative nausea and vomiting in patients undergoing middle ear surgery.
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Abstract (Original Language): 
Amaç: Bu çalışmada orta kulak cerrahisinde proflaktik uygulanan ondansetron ve haloperidol'ün pos-toperatif bulantı-kusma üzerine etkinliklerinin karşılaştırılması amaçlandı. Gereç ve Yöntem: Genel anestezi altında orta kulak cerrahisi geçirecek olan 40 hasta rastgele iki gruba ayrılıp, anestezi indüksi-yonundan 5 dakika önce ya intravenöz (IV) 2 mg haloperidol (Grup I) ya da IV 4 mg ondansetron (Grup II) verildi. Anestezi indüksiyonunda standart genel anestezi uygulandı. Postoperatif dönemde ilk 24 saat içinde bulantı-kusma verbal deskriptif skala ile değerlendirildi. Bulgular: Bulantı-kusma skoru açısından gruplar arasında istatistiksel olarak anlamlı farklılık bulunmadı (p>0.05). Bulantı-kusma görül¬me sıklığı ve ek antiemetik gereksinimi her iki grupta da istatistiksel olarak anlamlı değildi (p>0.05). Yan etki açısından da gruplar arasında fark yoktu (p>0.05). Sonuç: Orta kulak cerrahisi geçirecek hastalar¬da postoperatif bulantı-kusmayı önlemede 2 mg haloperidol'ün, 4 mg ondansetron kadar etkili oldu¬ğu gösterilmiştir.
FULL TEXT (PDF): 
PDF icon arastirmax-orta-kulak-cerrahisinde-postoperatif-bulanti-kusmanin-onlenmesinde-ondansetron-haloperidolun-etkilerinin-karsilastirilmasi.pdf
  • 1
25-30
  • Turkish

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