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PİLOMATRİKS KARSİNOMA

Pilomatrix carcinoma

Journal Name:

  • Selçuk Tıp Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
Aim: It was aimed to discuss a rare case which was diagnossed as pilomatrix carcinoma. Case Re-port: We report the case of a 50-year- old man with a pilomatrix carcinoma in his left forearm. In his history the patient announced taht the lesion had developed one year ago, and its size had ex¬panded rapidly after the first six- month period. Diagnosis of malignant pilomatricoma is essentially histopathological .The tumor was composed of pleomorphic basaloid cells with prominent nucleoli and frequent atypical mitoses accompanied by central areas with keratotic materials, shadow cells, and foci of necrosis. Vascular or perineural infiltration was not observed. The patient remained dise¬ase-free at the 22 months follow- up. Conclusion: Pilomatrix carcinoma is a neoplasm of low-gra¬de malignancy that should be distinguished from the conventional pilomatrixoma and its variants. Clinicians and pathologists should be aware of the occurrence of pilomatrix carcinoma because of its potential for distant metastases. We reviewed the literature and comment on the histopathologic differences from other cutaneous tumors.
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Abstract (Original Language): 
Amaç: Pilomatriks karsinoma tanısı konulan bir olgunun, nadir görülmesi nedeniyle tartışılması amaçlandı. Olgu Sunumu: 50 yaşında erkek hastada, sol ön kolunda yerleşim gösteren pilomatriks karsinoma olgusunu sunduk. Hasta hikayesinde lezyonun bir yıl önce geliştiği, ilk 6 aydan sonra bo-yutlarının hızla arttığı bildirildi. Pilomatriks karsinoma tanısı başlıca histopatolojik olarak verilir. Tümör, sıklıkla atipik mitozis gösteren, nükleolusları belirgin pleomorfik hücrelerden oluşmakta ve santralde keratotik materyal, gölge hücreleri, ve nekroz alanları ile karakterizeydi. Damar veya sinir infiltrasyo-nu görülmedi. Hasta 22 aydır lezyondan arınmış olarak izlenmektedir. Sonuç: Pilomatriks karsinoma düşük dereceli bir tümör olup, pilomatriksoma ve tiplerinden ayırımı yapılmalıdır. Klinisyenler ve pa¬tologların uzak metastaz potansiyeli yönünden, bu olgulara dikkatli yaklaşımı gerekmektedir. Literatürü gözden geçirerek olgunun diğer deri tümörleri ile ayırıcı tanısını tartıştık.
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  • 1
35-37
  • Turkish

REFERENCES

References: 

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