You are here

Akut Koroner Sendromlu Hastalarda Majör Risk Faktörlerinin ve Laboratuvar Parametrelerinin Değerlendirilmesi

Evaluation of Risk Factors and Laboratory Parameters in Patients of Acute Coronary Syndrome

Journal Name:

Publication Year:

Abstract (2. Language): 
Objective: Cardiovascular diseases are the leading causes of morbidity and mortality in both developed and developing countries. In this study, patients with acute coronary syndrome in terms of classic risk factors (age, gender, dyslipidemia, hypertension, diabetes Mellitus, etc) versus laboratory parameters were examined. Material and Methods: 370 patients hospitalized with acute coronary syndrome in the coronary intensive care unit were recruited and clinical features and also laboratory values thought to be related to acute coronary syndrome were evaluated. Results: Age interval of the patients was 26-91 years (mean 63). The prevalence of diabetes was 31% in males and 42 % in females, and that of hypertension was 65.2% in males and 43.1% in females. Mean total cholesterol level was 180 mg/dL, and mean LDL cholesterol level was 113 mg/dL. Mean leukocyte value was significantly high in patients with ST-elevation MI (10,900/mm3) compared with non-ST elevation MI (10,000/mm3) and unstable angina pectoris (9,200/mm3) (p=0.013). Conclusion: Acute coronary syndrome is one of the risk factors for hypertension, the highest rates were seen in the study group.
Abstract (Original Language): 
Amaç: Kalp ve damar hastalıkları, günümüzde gelişmiş ve gelişmekte olan ülkelerde başta gelen morbidite ve mortalite nedenidir. Bu çalışmada, akut koroner sendrom tanısı konan hastaların klasik risk faktörleri (yaş, cinsiyet, hiperlipidemi, hipertansiyon, diabetes mellitus) ve laboratuvar parametreleri incelenmiştir. Gereç ve Yöntem: Bir eğitim araştırma hastanesi koroner yoğun bakım servisinde akut koroner sendrom (AKS) tanısıyla takip edilen 370 hastanın klinik özellikleri ve AKS ile ilişkili olabileceği düşünülen laboratuvar değerleri incelendi. Bulgular: Hastaların yaş aralığı 26-91 (ortalama 63) bulundu. Diabetes Mellitus prevalansı erkeklerde %31, kadınlarda %42 olarak saptandı. Kadınların %43,1'inde, erkeklerin %65,2'sinde hipertansiyon tespit edildi. Ortalama total kolesterol oranı 180 mg/dl, ortalama LDL kolesterol oranı 113 mg/dl olarak bulundu. ST elevasyonlu miyokard enfarktüsünde (MI) ortalama lökosit değeri (10,900/mm3), non-ST elevasyonlu MI (10,000) ve unstabil angina pektorisli hastalara (9,200/mm3) oranla belirgin derecede yüksek saptandı (p=0,013). Sonuç: Akut koroner sendrom için risk unsurlarından biri olan hipertansiyon, çalışma grubunda en yüksek oranda görüldü
5
11

REFERENCES

References: 

1. Van de Werf F, Ardissino D, Betriu A et al. Management of Acute Myocardial Infarction Inpatients Presenting with ST-segment Elevation The Task Force on the Management of Acute Myocardial Infarction of the European
Society of Cardiology. Eur Heart J 2003;24:28-66.
2.
Onat A. TEKHARF Çalışması 2009. Onsekiz Yıllık İzleme Deneyimine Göre Türk Erişkinlerinde Kalp Sağlığı. http://tekharf.org/2009.html internet adresinden 05.05.20154 tarihinde erişilmiştir.
3. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA
2001;285:2486-97.
4. Basic Pathology, Kumar, Cotran, Robbins Türkcesi, Nobel Tıp Kitabevleri Ltd Şti 2010;
283-9.
5. Charles H, Hennekens PH. Increasing Burden of Cardiovascular Disease. Current Knowledge and Future Firections for Research on Risc Factors. Circulation 1998;97:1095-1102.
6. Anand SS, Islam S, Rosengren A et al. Risk Factors for Myocardial Infarction in Women and Men: Insights from the INTERHEART study. Eur Heart J 2008;29(7):932-40.
7. Haffner SM, Letho S, Ronnemaa T, et al.
Mortality From Coronary Heart Disease in Subjects With Type 2 Diabetes And in Nondiabetic Subjects With And Without Prior Myocardial Infarction. N Eng J Med 1998;
339:229-34.
8. Stratton JR, Chandler WL, Schwartz RS, et al.
Effects of Physical Conditioning on Fibrinolytic Variables and Fibrinogen in Young and Old Healthy Adults. Circulation 1991;83:1692-7.
9. Ceylan Y, Kaya Y, Tuncer M. Akut Koroner Sendrom Kliniği ile Başvuran Hastalarda Koroner Arter Hastalığı Risk Faktörleri. Van Tıp
Dergisi 2011;18(3):147-54.

Thank you for copying data from http://www.arastirmax.com