You are here

Geriatrik yaş grubunda çimentolu kalça protezi uygulamasının santral sıcaklık ve hemodinamik değişikliklere etkisi

The Effects of Cemental Hip Prostheses on Core Temperature and hemodynamic changes in Geriatric Patients

Journal Name:

Publication Year:

Abstract (2. Language): 
Surgical treatment of collum femoris fractures can be managed by total hip prosthesis with or without cement. We investigated whether the local increase of cement temperature during preparation causes a systemic body temperature increase and the its hemodynamic system. effects. Twenty geriatric cases older than 60 years planned for total hip prosthesis by using bone cement were included in the study. Noninvasive cardiac moni-torization was carried out. Systolic and diastolic arterial pressures, hearth rate and peripheral oxygen saturation were recorded. After anesthesia induction with propofol 0.2 mg kg-1 cisatracurium 0.1 mg kg-1 intuba¬tion was performed. Anesthesia was maintained with sevoflurane 2-3% in O2 %50 and N2O 50%. Volume-con¬trolled mechanical ventilation was applied with a tidal volume of 10 ml kg-1 and respiratory frequency of 12 min-1. Following intubation, core body temperature was measured by a temperature probe placed through 2/3 distal tip of the esophagus. Datas were recorded within 15 minutes intervals before and after cement (methylmethacrylate) application, temperature and hemodynamic datas were recorded at every 3 minutes during a period of 9 minutes. Datas were evaluated by paired samples t-test and p>0.05 was accepted as insignificant, p<0.05 as significant and p<0.0001 as highly significant. Core temperature changes were not sta¬tistically significant during the operation and bone cement application period. The hemodynamic changes were found to be statistically significant but clinically between acceptable ranges. We concluded that in bone cement used total hip prosthesis operations stable hemodynamic conditions and no change in core tempera¬ture are observed by using noninvasive monitorization.
Abstract (Original Language): 
Femur boyu n kırıklarının cerrahi tedavisinde protez uygulaması, çimentolu veya çimentosuz olarak yapılabilmektedir. Çimentonun hazırlanışı sırasında lokal olarak artan çimento ısısının sistemik bir sıcaklık artışına yol açıp açmadığı ve bu olası etkinin hemodinamik sistem üzerine olan etkileşimini araştırdık. Femur boyun kırığı nedeniyle çimento kullanılarak total kalça protezi uygulanacak geriatrik yaş grubuna giren 60 yaş üzeri 20 olgu çalışmaya alındı. Kardiak noninvaziv monitörizasyon uygulandı. Sistolik, diastolik arter basıncı, kalp atım hızı ve periferik oksijen satürasyonu değerleri kaydedildi. Anestezi indüksiyonu 0.2 mg kg-1 propofol ve 0.1 mg kg-1 cisatracurium ile gerçekleştirildi ve endotrakeal entübasyon yapıldı. 10 ml kg-1 tidal volümle 12 dk-1 frekans altında volüm kontrollü mekanik ventilasyona başlandı. Anestezi idamesi için % 2-3 sevofluran % 50 O2 + % 50 N2O kullanıldı. Entübasyon sonrası özefagus ısı probu özefagusun 2/3 alt kısmına gelecek şekilde yerleştirilerek devamlı santral sıcaklık monitörize edildi, veriler 15 dk aralarla kaydedildi. Çimento (methylmethacrylate) kullanımı öncesi ve sonrasında 3 dk aralarla 9. dk kadar sıcaklık ve hemodinamik verileri kaydedildi. Veriler paired samples t-test ile değerlendirildi; p>0.05 anlamsız, p<0.05 anlamlı, p<0.0001 çok anlamlı olarak kabul edildi. Operasyon sırasında ve çimento uygulanan dönemde santral sıcaklık değişimleri istatistiksel olarak anlamsız düzeyde gerçekleşti. Hemodinamik sistemde ise istatistiksel olarak anlamlı fakat klinik olarak kabul edilebilir sınırlarda değişiklikler saptandı. Çimento kullanılan kalça protezi operasyon¬larında noninvaziv monitörizasyon ile hemodinamik sistemin stabil olarak izlendiği ve santral ısı değişiklik¬lerinin olmadığı düşüncesindeyiz.
10-14

REFERENCES

References: 

1. Barth RJ, Mule JJ, Spiess PJ, Rosenberg SA. Interferon gamma and tumor necrosis factor have a role in tumor regressions mediated by murine CD8+ tumor-infiltrating lymphocytes. J Exp Med 1991; 173: 647-58.
2. Itoh K, Platsoucas DC, Balch CM. Autologous tumor-spe¬cific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas: activation by interleukin 2 and autol-ogous tumor cells and involvement of the T cell receptor. J Exp Med 1988; 168: 1419-1441.
3. Topalian SL, Solomon D, Rosenberg SA. Tumor-specific cytolysis by lymphocytes infiltrating human melanomas. J Immunol 1989; 142: 3714-3725.
4. Lamade WR, Friedl W, Schmid B, Meeder PJ. Bone cement implantation syndrome. A prospective randomised trial for use of antihistamine blockade. Arch Ürthop Trauma Surg 1995; 114:335-339.
5. Pitto RP, Blunk J, Kössler M. Transesophageal echocardio-graphy and clinical features of fat embolism during cement¬ed total hip arthroplasty. A randomized study in patients with a femoral neck fracture. Arch Ürthop Trauma Surg 2000; 120: 53-58.
6. Pitto RP, Koessler M, Kuehle JW. Comparison of fixation of the femoral component without cement and fixation with use of a bone-vacuum cementing technique for the prevention of fat embolism during total hip arthroplasty. A prospec¬tive, randomized clinical trial. J Bone Joint Surg Am 1999; 81: 831-843.
7. Xu JW, Konttinen YT, Lassus J, et al. Tumor necrosis fac¬tor-alpha (TNF-alpha) in loosening of total hip replacement (THR). Clin Exp Rheumatol 1996; 14: 643-648.
8. Clark DI, Ahmed AB, Baxendale BR, Moran CG. Cardiac output during hemiarthroplasty of the hip. A prospective, controlled trial of cemented and uncemented prostheses. J Bone Joint Surg Br 2001; 83: 414-418.
9. Lopez-Duran L, Garcia-Lopez A, Duran L, Hurtado J, Ruiz C, Rodrigo JL. Cardiopulmonary and haemodynamic changes during total hip arthroplasty. Int Orthop 1997; 21: 253-258.
10. Tryba M, Linde I, Voshage G, Zenz M. Histamine release and cardiovascular reactions to implantation of bone cement during total hip replacement. Anaesthesist 1991; 40: 25-32.
11 .Mitsuhata H, Saitoh J, Saitoh K, et al. Methylmethacrylate bone cement does not release histamine in patiens undergo¬ing prosthetic replacement of the femoral head. Br J Anaesth 1994; 73: 779-781.
12. Patel N, Smith CE, Pinchak AC, Hagen JF. Comparison of esophageal, tympanic, and forehead skin temperatures in
adult patients. J Clin Anesth 1996; 8: 462-468.
13. Kurz A, Sessler DI, Christensen R, Dechert M. Heat ba¬lance and distribution during the core-temperature plateau in anesthetized humans. Anesthesiology 1995; 83: 491-499.

Thank you for copying data from http://www.arastirmax.com