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Erişkin albino fare (mus musculus)' de bazı peptitlerin trakea, bronkus ve bronkulus mukozasındaki immunohistokimyasal lokalizasyonları

The ımmunohıstochernıcal localizations of some peptides in mucosa of trachea, bronchus and bronchulus in adult albino mouse (mus musculus

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, localizations of cells that secrete Calcitonin Gene-Related Peptide (CGRP), Serotonin (5-HT) and Endothelin (ET) in mucosa of trachea, bronchus and bronchulus (bronchulus verus and respiratorius) were purposed in adult albino mouse (Mus musculus). It was observed that intensity of CGRP-immunoreactive cells was more numerous than ET and 5-HT in trachea, bronchus, bronchulus respiratorius but these cells had similar distribution in bronchus verus. These peptides detected not only in the endocrine cells, but also in subepithelial nevre fibers of musculus transversus trachea, trachea, bronchus and bronchulus verus. Also these immunoreaktivities were found in some blood vessels, connective tissue, alveolar parenchima and tracheal ganglions.
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Abstract (Original Language): 
Bu çalışmada erişkin albino farelerde (Mus musculus) trakea, bronkus ve bronkulus (bronkulus verus ve respiratoryus) mukozasında kalsitonin gen ilişkili peptit (Calcitonin Gene-Related peptide=CGRP), serotonin (5-HT) ve endotelin (Endothelin=ET) salgılayan hücrelerin lokalizasyonlarının belirlenmesi amaçlanmıştır. CGRP immunoreaktif hücrelerin trakea, bronkus ve bronkulus respiratoryuslarda ET ile 5-HT'ye göre en fazla olduğu, fakat bu hücrelerin bronkulus veruslarda ise eşit dağılım gösterdiği tespit edildi. Bu peptitler, endokrin hücreler dışında musculus transversus trachea ile trakea, bronkus ve bronkulus verus subepitelyal sinir fibrillerinde de tespit edildi. Aynı zamanda bu immunoreaktivitelere bazı kan damarları, bağ dokusu, alveolar parenşim ve trakeal ganglionlarda da rastlandı.
FULL TEXT (PDF): 
PDF icon arastirmax-eriskin-albino-fare-mus-musculus-de-bazi-peptitlerin-trakea-bronkus-bronkulus-mukozasindaki-immunohistokimyasal-lokalizasyonlari.pdf
  • 3
21-25
  • Turkish

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