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Kasabach-Merritt Fenomeni yönetiminde vinkristin başarıyla kullanımı

Successful use of vincristine in the management of Kasabach-Merritt Phenomenon

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2012

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
A 2-month old boy with Kaposiform Hemangioendothelioma of the lumbosacral region invading the retroperitoneum was admitted with Kasabach-Merritt Phenomenon. After corticosteroid and interferon treatments failed with progression of the disease to a life threatening condition, vincristine monotreatment granted a rapid rise in platelet counts, fibrinogen levels and a resolution in the enlargement of the lesion. The remission was maintained and no adverse effects were observed during the treatment. Vincristin therapy may be suggested instead of multidrugs as first line therapy in patients with KMP.
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Abstract (Original Language): 
İki aylık erkek bebek, lumbosakral bölgede retroperitonu tutan Kaposiform Hemangioendothelioma ile, Kasabach Merrit penomeni (KMp) tanısı konarak hastaneye kabul edildi. Kortikosteroid ve interferon tedavileri hastalığın ilerlemesinde başarısız oldu. Vincristin mono tedavisi ile fibrinojen ve trombosit sayısı hızlı yükseldi, lezyon büyümesi geriledi. Remisyon sağlandı ve tedavi süresince yan etkiler gözlenmedi. Tedavisi kesildikten 6 ay sonra rölaps oluşmadı. KMp de çoklu ilaç tedavisi yerine ilk seçenek olarak vincristin tedavisi düşünülebilinir.
FULL TEXT (PDF): 
PDF icon arastirmax-kasabach-merritt-fenomeni-yonetiminde-vinkristin-basariyla-kullanimi.pdf
  • 2
55-58
  • Turkish

REFERENCES

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