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Benign Prostat Hiperplazisinde ve Prostat Adenokanserinde Prostatik tntraepiteliyal Neoplazi (PIN) Oranı

Prostatic Intraepithelial Neoplasia (PIN) Rate in Benign Prostatic Hyperplasia and Prostatic Adenocarcinoma

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1999

Key Words:

Keywords (Original Language):

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Abstract (2. Language): 
In this study, the prostatic tissue of 48 patients diagnosed as BPH and 27 patients diagnosed as prostatic adenocarcinoma were evaluated histopathologically and prostatic intraepithelial neoplasia (PIN) rates were determined. High grade PIN (PIN HI) was found 70 % in prostatic adenocarcinoma cases and 8 % in BPH cases. The difference between groups was statistically significant (p<0.005). These results were correlated with the studies done before. As a result, high grade PIN lesions were seen more in adenocancer cases and as shown in various studies, we agree that these lesions could be a premalign lesion of prostatic adenocarcinoma.
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Abstract (Original Language): 
48 Benign Prostat Hiperplazisi ve 27 prostat adenokanseri tanısı alan vakada prostat dokusu histopatolojik yönden incelendi ve prostatik intraepitelial neoplazi (P1N) oranları saptandı. Yüksek evre PIN (PIN III) kanserli olgularda % 70, benign olgularda ise % 8 oranında bulunduğu saptandı, İki grup arasındaki fark istatistiksel olarak anlamlı bulundu (p<0.005). Bu sonuçlar daha önce yapılan çalışmalarla uyumlu bulundu. Sonuçta, yüksek evre PIN lezyonlarının kanserli olgularda fazla görülmesi nedeni ile, bir çok çalışmada savunulduğu gibi, bu lezyonların prostat adenokanserinin bir premalign lezyonu olabileceği görüşüne varıldı
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  • 4
57-58
  • Turkish

REFERENCES

References: 

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