You are here

Home » Content

Fetal Döne m Boyunca Umbilikal Damarların Intraabdominal Bölümünün Işık Mikroskobu ile Araştırılması

Investigation of Intraabdominal Part of Umbilical Vessels by Light Microscope During the Fetal Period

Journal Name:

  • Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 1999

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
In this study, we aimed to investigate intraabdominal part of umbilical vessels in human fetuses during the fetal period by light microscope. We studied 90 (45 males, 45 females) human fetuses with no external anomaly and gestational ages between 10 and 40 weeks. Total vessel diameter, lumen diameter, wall thickness, tunica adventicia thickness, tunica muscularis thickness and vaso vasorum number of the microscopic cross section taken from umbilical vessels were determined. There were no pathologies related to umbilical vein and median umbilical ligaments. There are two Meckel's Diverticulum in the fetuses with no external pathology and anomaly. We determined two umbilical artery agenesis on the left and one umbilical artery agenesis on the right. Positive and meaningful correlation was found between the gestational age and morphometric measurements of umbilical vessels. We found differences between morphometric parameters in the second trimester, the third trimester andfull term period during the fetal period. The vessels diameters, lumen diameter, tunica muscularis thickness and tunica adventicia thickness were different between vena umbilicalis and arteriae umbilicalis (right and left). There were no differences related to vaso vasorum number and tunica adventicia thickness between groups in fetal period. With more expressions of morphometric parameters of umbilical vessels at each gestational age, determination of pathologies of umbilical vessels and some syndromes can be helped. We believe that the data about the development of the umbilical vessels obtained in our study will contribute to the studies on this issue in the future.
Bookmark/Search this post with
Abstract (Original Language): 
Çalışmamızda fetal dönem boyunca insan fetuslarmda umbilikal damarların intra abdominal bölümünün ışık mikroskubu ile araştırılması amaçlandı. Çalışmamızda yaşları 10-40 gebelik haftası arasında değişen eksternal patolojisi ve anomalisi olmayan 90 tane (erkek: 45, kız: 45) insan fetusunda çalışıldı. Umbilikal damarlardan alınan mikroskobik kesitlerde total damar çapı, lümen çapı, duvar, tunica adventicia, tunica muscularis kalınlığı ve vaso vasorum sayısı belirlendi. Vena umbilicalis ve ligamentum umbilicale mediana yapılarına ait herhangi bir patolojiye rastlanmadı. Eksternal patolojisi ve anomalisi olmayan fetuslarda iki tane meckel divertikülü tespit edildi. Ayrıca bu olgularda iki tane sol a. umbilicalis agenezisi, bir tane de sağ a. umbilicalis agenezisi olduğu tespit edildi. Gestasyonel yaş ile umbilikal damarların morfometrik parametreleri arasında pozitif yönde anlamlı ilişki bulundu. Fetal dönem boyunca ikinci, üçüncü trimestır ve full term dönemlerdeki morfometrik parametreler arasında farklılıklar bulduk. Sağ ve sol umbilikal arterler ile umbilikal ven arasında damar ve lumen çapı, tunica muscularis, tunica adventicia kalınlığı farklıydı. Fetal dönemde gruplar arasında tunica adventicia kalınlığı ve vaso vasorum sayısında farklılık bulunamadı. Gestasyonel yaşlara göre umbilikal damarlara ait morfometrik parametrelerin daha fazla tanımlanması; umbilikal damar patolojilerinin ve bazı sendromların belirlenmesinde yardımcı olabilir. Çalışmamadaki umbilikal damarların gelişimi hakkında belirlenen bilgilerin daha sonra yapılacak çalışmalara katkıda bulunacağına inanmaktayız.
FULL TEXT (PDF): 
PDF icon arastirmax-fetal-done-m-boyunca-umbilikal-damarlarin-intraabdominal-bolumunun-isik-mikroskobu-ile-arastirilmasi.pdf
  • 4
5-10
  • Turkish

REFERENCES

References: 

1- Sadler TW. hangman's Medical Embryology. Baltimore: Williams & Wilkins. 1985; 58-132.
2- Collins P. Embryology and development, Neonatal anatomy and growth. In: Williams PL, Bannister LH, Berry MM, Collins P, Dyson M, Dussek JE, Ferguson MWJ. Gray's Anatomy (38th Ed) London: Churchill Livingstone. 1995; 91-342.
3- Ullrich K, Bohm N. Early embryonal maldevelopment of the umbilical cord with defect of the abdom inal wall and severe body malformations. Beitr Pathol 160 (3): 286-297, 1977.
4- Heifetz SA. Single umbilical artery. Perspect Pediatr Pathol 1984; 8(4): 345-78.
5- Byrne J, Blanc WA. Malformations and chromosome anomalies in spontaneously aborted fetuses with single umbilical artery. Am J Obstet Gynecol 1985; 151: 340-2.
6- Leung AK, Robson WL. Single umbilical artery. A report of 159 cases. Am J Dis Child. 1989; 143(1): 108-11.
7- Moore KL, Persaud TVN. The Develophing Human (Clinically Oriented Embryology). 6th
Ed. Philadelphia: WB Saunders. 1998; 107¬215.
8- Taeusch HW. Major influences on fetal growth and development. In: Taeusch HW, Ballord RA, Avery ME. Diseases of The Newborn. Philadelphia: WB Saunders. 1991; 23-98.
9-Abuhamad AZ, Shaffer W, Mari G, Copel J A, Hobbins JC, Evans AT. Single umbilical artery: Does it matter which artery is missing? Am J Obstet Gynecol 1995; 173: 728-32.
10- Saraçoğlu
F.
Fetal Tanı ve Tedavi. Ankara: Güneş Kitabevi. 1998; 55-72.
11- Manning FA. Ultrasound in perinatal medicine. In: Creasy RK, Resnik R. Maternal Fetal Medicine. Philadelphia: WB Saunders. 1989; 195-253.
12- Junqueira LC, Carneiro J, Kelley RO. Basic histology, California Appleton & Lange 1992; 216-31.
13- Gabella G. Cardiovascular system. In: Williams PL, Bannister LH, Berry MM, Collins P, Dyson M, Dussek JE, Ferguson MWJ. Gray's Anatomy (38th Ed). London: Churchill Livingstone. 1989; 1451-626.
14- Weickert U, Reitnauer K, He JP, Ertan AK, Schmidt W, Remberger K. Placenta morphology and Doppler ultrasound of umbilical cord vessels in premature infants. Zentralbl Gynakol 1999; 121(1): 7-13.
15- Bruch JF\ Sibony O, Benali K, Challier JC, Blot P, Nessmann C. Computerized microscope morphometry of umbilical vessels from pregnancies with intrauterine growth retardation and abnormal umbilical artery Doppler. Hum Pathol 1997; 28(10): 1139-45
16- Barta JL, Comino DR, Gonzalez MC, Lopez I, Arrabal J. Umbilical blood flow and neonatal morphometry: a multivariate analysis. Eur J Obstet Gynecol Reprod Biol 1998; 79(1): 27¬33.
17- Raio L, Ghezzi F, Di Naro E, Gomez R, Franchi M, Mazor M, Bruhwiler H. Sonographic measurement of the umbilical cord and fetal antropometric parameters. Eur J Obstet Gynecol Reprod Biol 1999; 83(2): 131-5.

Thank you for copying data from http://www.arastirmax.com