You are here

VÜCUT KOMPOZİSYONU DEĞİŞİKLİKLERİNİ SAPTAMADA DUAL-ENERJİ X-RAY ABSORBSİYOMETRİ VE BİYOELEKTRİK İMPEDANS; BİR HEMODİYALİZ SEANSININ ETKİSİNİ SAPTAMA İKİ YÖNTEMİN KARŞILAŞTIRMALI ANALİZİ

THE COMPARISON OF DUAL-ENERGY X-RAY ABSORBTIOMETRY AND BIOELECTRIC IMPEDANCE ANALYSIS IN DETERMINATION OF BODY COMPOSITION IN HEMODIALYSIS PATIENTS

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
Chronic renal failure causes changes in body composition. Dual-Energy X-Ray Absorbsiometry (DEXA) and bioelectric impedance analysis (BIA) are the techniques to evaluate body composition in chronic renal failure. In the present study, we aimed to perform comparative analysis of DEXA and BIA in determination of minor changes in body composition occurring during single dialysis session. Each patient was weighed and body composition was measured by DEXA and BIA before and after dialysis. When measurements before and after dialysis by DEXA were considered, changes in fat mass and bone mineral content were not statistically significant, whereas lean body mass and total weight measurements before and after dialysis differed significantly. BIA was considered, fat mass, lean body mass and water content before and after dialysis were found to be statistically significantly different. When results obtained by DEXA BIA were compared differences in means of EM and LBM were not statistically significant and they were found to be positively correlated. As a conclusion; DEXA is a quite sensitive technique in determination of FM, LBM and bone mineral content and can be used in dialysis patients to determine short and long term changes in body composition. Despite BIA is less reliable in determination of body composition, it can be still used in determination of dry weight in conjunction with clinical parameters since it is a noninvasive and easy to perform technique at bedside.
Abstract (Original Language): 
Kronik böbrek yetmezliği (KBY), vücut kompozisyonunda değişiklikler oluşturan önemli bir süreçtir. Dual-Enerji X-Ray Absorbsiyometri (DEXA) ve Biyoelektrik impedans analiz (BİA), KBY hastalarında vücut kompozisyonunu değerlendirmede kullanılan yöntemlerdir. Çalışmamızda bir diyaliz seansı sırasında oluşan küçük vücut kompozisyonu değişikliklerini saptamada DEXA ve BİA ölçümlerinin karşılaştırmalı analizini yapmayı amaçladık. Hastalar diyaliz öncesi ve sonrası elektronik tartı ile tartıldı, DEXA ve BİA ile vücut kompozisyonu ölçümleri yapıldı. DEXA ile diyaliz öncesi ve sonrası değerler karşılaştırıldığında kemik mineral içerik ve yağ dokusunda değişiklik saptanmazken, yağsız vücut kulesindeki azalma miktarı 2.53 kg idi ve elektronik tartı ile saptanan değer ile arasında korelasyon mevcuttu (r= 0.6923). BİA ile elde edilen sonuçlarda diyaliz öncesi ve sonrası yağ miktarı, yağsız doku miktarı, su miktarı değerlerinde istatistiksel olarak anlamlı değişiklikler saptandı (p<0.05). DEXA 'nın yağ miktarı, yağsız vücut kitlesi ve kemik doku miktarını belirlemede oldukça duyarlı bir yöntem olduğu kanısına vardık. BİA ise, daha az güvenilir bir yöntem olmakla birlikte uygulamadaki kolaylıkları nedeniyle klinik parametrelerle birlikte kullanılabilir sonucuna vardık.
FULL TEXT (PDF): 
244-248

REFERENCES

References: 

1. Degoulet P, Legrain M, Reach I, et al. Mortality risk factors in patients treated by chronic hemodialysis. Nephron 1982: 31: 103-110.
2. Lowrie EG, Lew NL. Death risk in hemodialysis patient: the predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis 1990: 15:458-482.
3. Oksa H, Ahonen K, Pasternak A, et al. Malnutrition in hemodialysis patient. Scand J Urol Nephrol 1991: 25: 157¬161.
4. Durnin JVGA, Womersley J: Body fat assessed from total body density and its estimation from skinfold thickness: Measurements on 481 men and women aged from 17 to 72 years.Br J Nutr 1974; 32: 77-97.
5. Zillikens MC, Conway JM: Antropometry in blacks: Applicability of generalized skinfold equations and differences in fat patterning between blacks and whites. Am
J Clin Nutr 1990; 52:45-51
6. Heymsfıeld SB, Wang Z, Baumgartner RN, et al. Human body composition: Advances in models and methods. Annu Rev Nutr 1997: 17: 527-558.
7. Roubenhoff R, Kehajas JJ, Dawson-Hughes B, et al. Use of
dual-energy x-ray absorptiometry in body composition studies: Not yet a "gold standard.". Am J Clin Nutr 1993: 58:589-591.
8. Morgan M, Madden A. The assessment of body composition in patients with cirrhosis. Eur J Nucl Med 1995:23:213-225.
9. Pietrobelli A, Formica C, Wang Z, et al: Dual- energy x-ray absorptiometry body composition model: Review of
physical concepts. Am JPhysiol 1996: 271: E941-E951.
10. Baumgartner RN, Chumlea WC, Roche AF. Impedance for
body composition. Exerc Sport Sci Rev 1990: 18: 193-224.
11. Bergström J. Why are dialysis patients malnourished? Am J Kidney Dis 1995: 26: 229-241.
12. De Vita MV, Rasenas LL, Bansal M, et al. Assessment of renal osteodystrophy in hemodialysis patients. Medicine 1992:71:284-290.
13. Gabay C, Ruedin P, Slosman D, et al. Bone mineral density in patients with end-stage renal failure. Am J Nephrol 1993: 13:115-123.
14. Georgiou E, Virvidakis K, Douskas G, et al. Body composition changes in hemodialysis patients before and after hemodialysis as assessed by dual- energy x-ray
absorptiometry. Metabolism 1997: 46: 1059-1062.
15. Metry G, Malimin H, Wikstrom B, et al. Proportional changes in body fluid with hemodialysis evaluated by dual-energy x-ray absorbtiometry and transthoracic bioimpedance with particular emphasis on the thoracic
region. Artificial Organs 1997: 21: 969-976.
16. Woodrow G, Oldroyd B, Tumey JH, et al. Influences of changes in peritoneal fluid on body- composition measurements by dual- energy x-ray absorptiometry in patients receiving continuous ambulatory peritoneal
dialysis. Am J Clin Nutr 1996: 64:237-241.
17. Pritchard JE, Nowson CA, Strauss BJ, et al. Evaluation of dual energy x-ray absorptiometry as a method of measurements of body fat. Eur J Clin Nutr 1993: 47: 216¬228.
18. Horber FF, Thomi F, Casez JP, et al. Impact of hydration status on body composition as measured by dual-energy x-ray absorptiometry in normal volunteers and patients
haemodialysis. Br J Radiol 1992: 65: 895-900.
19. Woodrow G, Oldroyd B, Turney JH, et al. Four-component model of body composition in chronic renal failure comprising dual-energy x-ray absorptiometry and measurement of total body water by deuterium oxide
dilution. Clin Scie 1996: 91: 763-769.
20. Stall SH, Ginsberg NS, De Vita MV, et al. Comparison of
five body composition methods in peritoneal dialysis patients. Am JClin Nutr 1996: 64: 125-130.
21. Katzarski K, Charra B, Laurent G, et al. Multifrequency bioimpedance in assessment of dry weight in hemodialysis. Nephrol Dial Transplant 1996: 11: 26-30.
22. Fisch BJ, Spiegel DM. Assessment of excess fluid distribution in chronic hemodialysis patients using bioimpedance spectroscopy. Kidney Int 1996: 49: 1105¬1109.
23. Ho LT, Kushner RF, Schoeller DA, et al. Bioimpedance analysis of total body water in hemodialysis patients.
Kidney Int 1994: 46: 1438-1442.
24. Sergi G, Bussolotto M, Perini P, et al. Accuracy of bioelectircal impedance analysis in estimation ol extracellular space in healthy subjects and in fluid retention states. Ann NutrMetab 1994: 38: 158-165.
25. Bioelectrical impedance analysis in body composition measurement. NIH Tecnol Assess Statement 1994: Dec 12¬14: 1-35.
26. Abrahamsen B, Hansen TB, Hogsberg IM, et al. Impact of hemodlysis on dual x-ray absorbtiometry, bioelectrical impedance measurements, and anthropometry. Am J Clin
Nutr 1996: 63: 80-86.
27. Woodrow G, Oldroyd B, Turney JH, et al. Measurement of total body water by bioelectrical impedance in chronic renal failure. Eur J Clin Nutr 1996: 50: 676-681.
28. Kong CH. Determination of total body water in uraemic patient by bioelectrical impedance. Nephrol Dial Transplant 1993:8:716-719.

Thank you for copying data from http://www.arastirmax.com