You are here

Home » Content

RENAL TRANSPLANTASYON SONRASI GELİŞEN PSÖDOTÜMÖR SEREBRİ

PSEUDOTUMOR CEREBRI DEVELOPMENT AFTER RENAL TRANSPLANTATION

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Pseudotumor cerebri (PTC) is a syndrome with increased intracranial pressure (>200mmH2O) and characterized by headache, loss of vision and papiledema. Many drugs and diseases may lead to this clinical picture and Cyclosporin A is one of them. A 17-year-old case with PTC who had undergone cadaveric renal transplantation due to chronic renal failure secondary to reflux nephropathy after six months' duration of hemodialysis program and who was on CyA, azathioprine and steroid as immune suppressants for 3 years after transplantation is reported hereby. It should be kept in mind that the patients who undergo renal transplantation and who are on treatment modalities including CyA are at risk of PTC and delay of prompt treatment may lead to blindness.
Bookmark/Search this post with
Abstract (Original Language): 
Psödotümör serebri (PTS) intrakranial basınç artmasıyla (>200 mmHıO) birlikte baş ağrısı, görme alanı kaybı ve papil ödemi ile karakterize bir sendromdur. Bir çok hastalık ve ilaç kullanımı bu tabloya yol açmaktadır ve Siklosporin A (CyA) da bu ajanlardan biridir. Burada reflü nefropatisine sekonder kronik böbrek yetmezliği sebebi ile 6 ay hemodiyaliz programında izlenip kadaverik renal transplantasyon yapılan, CyA, azothioprine ve steroidden oluşan immiinsupressif tedavi protokolü uygulanırken transplantasyondan 3 yıl sonra PTS tablosu ile başvuran 17yaşında bir olgu sunulmuştur. Renal transplantasyon uygulanan ve CyA içeren tedavi protokolü uygulanan olgularda PTS tablosunun gelişebilecek komplikasyonlardan biri olduğu bilinmeli, tedavideki gecikmenin görme kaybına yol açacağı unutulmamalıdır.
FULL TEXT (PDF): 
PDF icon pdf_tndt_436.pdf
  • 2
109-111
  • Turkish

REFERENCES

References: 

1. Corbett J, Mehta M. Cerebrospinal fluid pressure in normal obese subjects and patients with pseudotumor cerebri. Neurology 1983;33:1386-1388.
2. Baker RS, Baumann RJ, Buncic JR. Idiopathic intracranial hypertension (pseudotumor cerebri) in pediatric patients. Pediatr Neurol 1989;5:5-11.
3. Rodriguez E, Delucchi A, Cano F. Neurotoxicity caused by cyclosporin A in renal transplantation in children. Rev Med Chil 1992;120(Suppl 3):3OO-3O3.
4. Katz B. Disk edema subsequent to renal transplantation. Surv Ophthalmol 1997;41
(Suppl4):315-320.
5. Obeid T, Awada A, Huraib S, Quadri K, Abu-Romeh R. Psedotumor cerebri in renal transplant recipients: a diagnostic challenge. J
Nephrology 1997;10(Suppl 5):258-260.
6. Wall M. Idiopathic intracranial hypertension.
Neurologic Clinics 1991;9:73-95.
7. Sheth KJ, Kivlin JD, Leichter HE.
Pseudotumor cerebri with vision impairment in two children with renal transplantation.
Pediatr Nephrol 1994;8:91-93.
8. Gonzales Vincent M, Diaz MA, Madero L. Pseudotumor cerebri" following allogeneic bone marrow transplantation (BMT). Ann
Hematol 2001;80(Suppl 4):236-237.
9. Showengerdt KO Jr, Gajarski JR, Denfield S.
Progressive visual deterioration leading to blindness after pediatric heart transplantation. Tex Heart Inst J. 1993;20( Suppl 4):299-303.

Thank you for copying data from http://www.arastirmax.com