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HEMODİYALİZ VE SÜREKLİ AYAKTAN PERİTON DİYALİZİ HASTALARINDA KAN BASINCI KONTROLÜNÜN YETERLİLİĞİNİN KARŞILAŞTIRILMASI

COMPARISION OF BLOOD PRESSURE CONTROL IN PATIENTS WITH HEMODIALYSIS AND CONTINIOUS AMBULATORY PERITONEAL DIALYSIS

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2003

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Hypertension (HT) continues to be one of the major causes of cardiovascular morbidity and mortality in end stage renal disease (ESRD) patients. It is assumed that blood pressure (BP) should, theoretically, be better-controlled in continuous ambulatory peritoneal dialysis (CAPD) patients compared to hemodialysis (HD) patients. However, data in literature about BP control in CAPD and HD patients is controversial. In this study, we investigated the adequacy of BP control in groups of HD and CAPD patients matched for age, sex, and primary cause of end stage renal disease. Blood pressure measurements were performed by ambulatory blood pressure monitoring (ABPM) device for 48-hours in HD patients and for 24-hours in CAPD patients. Twenty five HD patients (12 female, 13 male; mean age 47.1 ± 14.8 years; mean duration of dialysis, 39.1 ± 51.4 months), and 25 CAPD patients (12 female, 13 male; mean age 46.7 ± 14.1 years; mean duration of dialysis 27.5 ± 16.1 months) were included in the study. Twelve (%48) patients in HD group and 16 (%64) patients in CAPD group were on antihypertensive treatment (p=0.51). Mean 24-hour, day time and night time systolic (SBP) diastolic (DBP) blood pressures were significantly higher in CAPD patients compared to HD patients. Proportion of patients with uncontrolled DBP (24-h DBP >85 mm Hg) was higher in CAPD patients than HD patients (72% vs 32%, p=0.01). In conclusion, our results demonstrate that although the number of antihypertensive drugs used to control BP were similar in HD and CAPD patients, BP is better controlled in HD patients compared to that of CAPD patients.
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Abstract (Original Language): 
Son dönem böbrek yetmezliği hastalarında hipertansiyon (HT) en önemli morbidite ve mortalite sebeplerinden biri olmaya devam etmektedir. Sürekli ayaktan periton diyalizi (SAPD) hastalarında kan basıncı (KB) kontrolünün hemodiyaliz (HD) hastalarına göre daha yeterli olabileceği belirtilmektedir. Ancak, HD ve SAPD hastalarında KB kontrolü ile ilgili veriler çelişkilidir. Çalışmamızda, yaş, cinsiyet, ve böbrek yetmezliği sebepleri eşleştirilmiş, HD ve SAPD hastalarında KB kontrolünün yeterliliği araştırılmıştır. Kan basıncı ölçümleri HD hastalarında 48 saat süreyle, SAPD hastalarında ise 24 saat süreyle ambulatuar kan basıncı monitörizasyon (AKBM) aleti ile yapıldı. Çalışmaya 25 HD hastası (13 erkek, 12 kadın; ortalama yaş 47.1.±14.8 yıl; ortalama diyaliz süresi 39.1 ± 51.4 ay ) ve 25 SAPD hastası (13 erkek, 12 kadın; ortalama yaş 46.7 ± 14.1 yd; ortalama diyaliz süresi 27.5 1 16.1 ay ) dahil edildi. HD grubunda 12 (%48) hasta, SAPD grubunda ise 16 (%64) hasta antihipertansif tedavi almakta idi (p=0.51). Ortalama 24-saat, gündüz ve gece periyodlarında sistolik (SKB) ve diyastolik (DKB) kan basınçları SAPD grubunda HD grubundan anlamlı olarak yüksekti. Yirmi dört saatlik KB ortalamaları dikkate alındığında, DKB kontrolsüz hasta oram (<85 mm Hg) SAPD hasta grubunda anlamlı olarak yüksekti (%72 ve %32; p=0.01). Sonuçlarımız benzer sayılarda antihipertansif ajan kullanmalarına rağmen HD hastalarında KB kontrolünün SAPD hastalarına göre daha iyi yapılabildiğini göstermektedir.
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  • 3
164-169
  • Turkish

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