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Van İlindeki Glomerülonefritlerin Epidemiyolojisi: 129 Vakanın Patolojik Bulguları

Epidemiology of Glomerulonephritis in the City of Van: Pathological Findings of 129 Cases

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Abstract (2. Language): 
Epidemiologies of nephropathies differ in different geographical and developmental areas. In order to determine the region's adult nephropathy profile, consecutive renal biopsies performed between January 1997 and December 2003 were reviewed. There were 129 cases (M 63, F 66, mean age 32.2±15.6), of which 115 had adequate biopsies. Lupus nephritis formed the largest diagnostic entity (23.3%). When lupus cases are excluded, the most common form of glomerulonephritis is membranoproliferative form (27.6%). While high lupus nephritis incidence may be due to our routine bi¬ opsy protocol for these patients, relatively higher incidence of MPGN may represent higher prevalences of different infections in the region.
Abstract (Original Language): 
Glomerülopatilerin sıklıkları bölgelerin coğrafyasına ve gelişmişliğine göre değişebilir. Bölgemizdeki erişkin nefropati profilini saptamak için Ocak 1997-Aralık 2003 arasında yapılan böbrek biyopsileri retrospektif olarak incelendi. Yüz yirmi dokuz olgunun (E 63, K 66, ort. yaş 32.2±15.6) 115'inde yeterli materyal elde edilebildi. Lupus nefriti en fazla görülen glomerülopati idi (%23.3). SLE çı¬ karıldıktan sonra yapılan sıralamada membranoproliferatif glomerülonefrit (MPGN) %27.6 ile en sık tanı konan glomerülonefrit olarak saptandı. Yüksek lupus nefriti insidansı, muhtemelen SLE tanısı almış hastalardaki rutin biyopsi yaklaşımımızdan kaynaklanmakta iken, MPGN'nin yüksek oranda bulunması ülkemiz şartlarında tanımlanamayan infektif ajanların glomerülonefrit patogenezinde halen önemli rol oynadığını düşündürmektedir.
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