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Hemodiyaliz Hastalarında Kardiyak Performans ile Bipedal Biyoimpedans Analiz Verileri Arasındaki İlişki

Relationship Between Bipedal Bioimpedance Analysis Data and Cardiac Performance in Patients on Maintenance Hemodialysis

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Abstract (2. Language): 
Total body water (TBW) has recently been recognized as having independent prognostic value in hemodialysis patients because of its relationship with hypertension and cardiac morbidity. The aim of this study is to investigate associations between TBW changes measured by bipedal bioelectrical impedance analysis (BP-BIA), and morpholo¬ gic and functional cardiac changes assessed by echocardiography in hemodialysis patients before and after the same dialysis session. Twenty clinically stable adult hemodialysis patients (13 males, 7 females; mean age [years]: 60 ± 15.6) who had been on regular dialysis treatment for at least six months were included in the study. We used BP-BIA and the Watson equations for estimating TBW before and after dialysis sessions. Echocardiographic measurements were perfor¬ med in pre- and post-dialysis periods. After dialysis, significant decreases in TBW-BP-BIA, TBW-W and body weight were observed. LVIDD, LVEDV, LVESV, LAD, RAD, SV and CO measurements were markedly decreased after dialysis sessions. Ejection fraction and heart rate did not change significantly after hemodialysis. TBW-BP-BIA values showed no correlation with cardiac chamber diameters and functions in pre- and post-dialytic periods. In hemodynamically stable patients having normal left ventricular functions, a reduction in TBW during dialysis causes a diminution in the diameter of cardiac chambers. BP-BIA, a simple method, can be used for TBW measurement. In addition, in this study, no correlation was observed between pre- and post-dialytic period cardiac chamber diameters and TBW-BP-BIA.
Abstract (Original Language): 
Son zamanlarda, total vücut suyunun (TVS) hipertansiyon ve kardiyak morbidite ile ilişkisi nedeniyle hemodiyaliz (HD) hastalarında prognostik önemi olduğu kabul edilmektedir. Bu çalışmanın amacı, HD hastalarında HD seansı öncesi ve sonrasında bipedal biyoelektrik impedans analizi (BP-BİA) ile ölçülen TVS değişiklikleri ve ekokardiyografi ile belirlenen morfolojik ve fonksiyonel kardiyak değişiklikleri değerlendirmektir. Bu çalışmaya, en az altı aydır düzenli HD tedavisi gören, klinik olarak stabil 20 erişkin HD hastası (13 erkek, 7 kadın; ortalama yaş [yıl]: 60 ± 15.6) alınmıştır. Diyaliz öncesi ve sonrasında TVS hesaplaması için Watson formülü (TVS-W) ve BP-BİA (TVS-BPBİA) kullandık. Ekokardiyografik ölçümler pre- ve post-diyaliz pe¬ riyotta yapıldı. Diyaliz sonrası vücut ağırlığı, T V S -W ve TVS-BP-BİA'da anlamlı düşüş gözlendi. Diyaliz seansı sonrası LVIDD, LVEDV, LVESV, LAD, RAD, SV ve CO ölçümleri belirgin şekilde düşüş gösterdi. Ejeksiyon fraksiyonu ve kalp hızında HD sonrasında anlamlı deği¬ şiklik olmadı. Pre- ve post-diyalitik periyotta TVS-BP-BİA değerleri, kalp odacığı çapları ve fonksiyonları ile korelasyon göstermedi. Normal sol ventrikül fonksiyonlarına sahip, hemodinamik ola¬ rak stabil hastalarda, diyaliz sırasında TVS'deki azalma kalp odacıklarının çaplarında küçülmeye neden olmaktadır. BP-BİA TVS ölçü¬ münde kullanılabilen basit bir yöntemdir. Bu çalışmada ayrıca, preve post-diyalitik periyotta kalp odacıkları çaplarında ve TVS-BP-BİA arasında korelasyon gözlenmedi.
FULL TEXT (PDF): 
71-75

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