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İnvazif Aspergilloza Bağlı Orbital Apeks Sendromu Olan Renal Transplant Alıcısı

A Renal Transplant Recipient With Orbital Apex Syndrome Due to Invasive Aspergillosis

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2005

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
A Turkish patient was evaluated because of loss of vision of the left eye at the second month after renal transplantation. The ophtal-mologic examination showed the involvement of IlIrd, IVth and Vlth cranial nerves and orbital apex syndrome was diagnosed. Further investigations showed the presence of acute inflammation in left eth¬moid and sphenoid paranasal sinuses. The results of the paranasal sinus endoscopy and pathological examination of the punch biopsies were consistent with invasive aspergillosis sinusitis. Cranial and orbital magnetic resonance images showed orbital sellulitis with the involvement of orbital apex. There was also cavernous sinus throm¬bosis and thrombosis of internal carotid arteria. The patient was treated with liposomal amphothericin B for 56 days and with itraconazole 200 mg/day for the maintenance therapy. A significant regression of the invasive sinusitis was achieved with this therapy. The patient is now on haemodialysis with good health.
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Abstract (Original Language): 
Renal transplantasyo n sonrası 2. ayda gelişen sol gözde görme bozukluğu nedeniyle değerlendirilen hastada 3, 4 ve 6. kraniyal sinir tutulumu ve orbital apeks sendromu saptanmış ve yapılan ileri tetkiklerde sol etmoid ve sfenoid sinüslerde akut inflamasyon saptanmıştır. Paranazal sinüs endoskopisi ve biyopsi sonuçları hastada invazif aspergilloz sinüziti olduğunu göstermiştir. Kraniyal ve orbital manyetik rezonans görüntülemeleri de inflamasyonun orbital apekse, kavernöz sinüse ve internal karotis arterine yayıldığını göstermiştir. Hasta 56 gün boyunca lipozomal amfoterisin B ile tedavi edilmiss ve idame tedavisinde günlük 200 mg itrakonazol kullanılmıştır. Hastada bu tedavi ile belirgin düzelme saptanmıştır. Hasta şu anda sağlıklı olarak hemodiyaliz programında izlenmektedir.
FULL TEXT (PDF): 
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  • 4
205-207
  • Turkish

REFERENCES

References: 

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