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Akut Böbrek Yetmezliği ve Sarılıkla Başvuran Bir Hastada Leptospiroz

Leptospirosis in a Patient With Acute Renal Failure and Jaundice

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Abstract (2. Language): 
Leptospirosis is a re-emerging infectious disease, affecting both animals and humans worldwide. Multiple organ involvement may be encountered in leptospirosis. Renal involvement is very common. We describe the patient with Weil's syndrome from central Anatolia in Turkey who presented with renal failure and jaundice. Illust¬rating the medical history, initial findings and clinical course, we po¬int out the importance and difficulties of early diagnosis and treat¬ment. This case indicates that leptospirosis presenting with renal fa¬ilure is a severe disease. The association of acute renal failure and jaundice should lead the clinician to suspect leptospirosis. Leptospirosis may be associated with mesangioproliferative glomerulonephritis most likely mediated by immune complexes, interstitial nephritis, or acute renal failure resulting from acute tubular necrosis.
Abstract (Original Language): 
Leptospiroz tüm dünyada görülen, insan ve hayvanları etkileyen infeksiyöz bir hastalıktır. Multipl organ tutulumu olabilir. Renal tutulum bu hastalıkta sıktır. Bu yazıda sarılık ve böbrek yetmezliği ile başvuran, Weil send-romu tanısı konan bir hastanın klinik özellikleri, erken tanı ve teda¬vinin önemi ve zorlukları anlatılmıştır. Leptospiroz şiddetli böbrek yetmezliği ile ortaya çıkabilir. Sarılıklı ve böbrek yetmezlikli hastada klinisyen leptospirozdan şüphelenmelidir. Leptospiroz, immün komplekslere bağlı mezangiyoproliferatif glomerülonefrit, interstis-yel nefrit veya akut tübüler nekroz ve sonucunda akut böbrek yet¬mezliğine neden olabilir.



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