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Otozomal Dominant Polikistik Böbre k Hastalığında Hipertansiyon ve Kardiyovasküler Sorunlar

Hypertension and Cardiovascular Problems in Autosomal Dominant Polycystic Kidney Disease

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Abstract (Original Language): 
Otozomal dominan t polikistik böbrek hastalığı i (ODPBH), her iki böbrekte kistik değişiklikler gös¬teren sistemik ve kalıtsal bir hastalıktır. Otozomal dominant polikistik böbrek hastalığı, en sık görülen kalıtsal böbrek hastalığıdır ve son dönem böbrek i yetersizliği (SDBY) olgularının %5-10'undan sorum- i ludur (1). Hipertansiyon, bu hastalıkta sık karşılaşı- j lan bir bulgu olup hastaların morbidİte ve mortalite- j sinde önemli bir rol oynar (2). Hipertansiyon, hasta- j ların yaklaşık %60'ında böbrek fonksiyonları bozul- i madan önce ortaya çıkar (2,3). Hipertansiyonu olan \ polikistik böbrek hastalarında böbrek fonksiyonları j daha hızlı bozulur (4). Ayrıca, hipertansiyon, bu | hastaların en sık ölüm nedeni olan kardiyovasküler | hastalıklar için önemli bir risk faktörüdür (5).
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REFERENCES

References: 

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Official Journal of the Turkish Society of Nephrology / Türk Nefroloji Diyaliz ve Transplantasyon Dergisi
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0 Hypertension and Cardiovascular Problems in Autosomal Dominant Polycystic Kidney Disease
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