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Otozomal Dominant Polikistik Böbrek Hastalığında Renal Replasman Tedavileri

Renal Replacement Therapies in Autosomal Dominant Polycystic Kidney Disease

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Abstract (Original Language): 
Otozomal dominant polikistik böbrek hastalığına CODPBH) bağlı son dönem böbrek yetmezliği (SDBY) genellikle 601ı yaşlarda gelişmektedir. ÖDPBH olan hastaların çoğunda uzun yıllar içerisinde glomerüler filtrasyon hızımla ilerleyici bir azalma gözlenmektedir. Hastaların yaklaşık yarısı SDBY nedeniyle diyaliz tedavisine İhtiyaç göstermektedir (1). j Diğer nedenlere bağlı böbrek vctmezlikli hastalara göre daha ivi diyaliz sonuçlan olduğu bildirilmektedir (2). Son dönem böbrek yetersizliği gelişimi 40 yaşın j alımda oldukça nadir olup, hastalığın progresyo- I nunda değişik faktörler rol oynamaktadır (3,4). j Genç bir hastada polikistik böbrek tanısı konduğun- ; da daha erken SDBY gelişeceği bildirilmektedir. Otuz yaşından önce tanı konulması durumunda renal sun inin 30 yaşın üzerinde tanı konulanlara göre. 10 yıl daha kısa olduğu saptanmıştır (5). Erkek hastalarda kadın hastalara göre daha hızlı bir seyir gözlenmekte ve diyalize başlama ?-6 yıl daha erken j oluşmakladır (1,6-9).
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Türk
Nefroloj
i Diyaliz ve Transplantasyon Dergisi /Official Journal of the Turkish Society of Nephrology
Otozomal Dominant Polikistik Böbrek Hastalığında Renal Replasman Tedavileri %
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Küçü
k M. Istanbul Tıp Fakültesi Nefroloji Bilim Dalı Transplantasyon polikliniğince izlenen hastaların demografik analizi ve greft sağkahmına etki eden faktörlerin değerlendirilmesi. Yan dal uzmanlık tezi, İstanbul. 2003.

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