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2001-2007 Döneminde Nefrotik Sendromlu 152 Hastanın Analizi

Analysis of 152 Patients with Nephrotic Syndrome in the Period between 2001 and 2007

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Abstract (2. Language): 
The frequency of glomerulonephritis (GN) may vary depend¬ing on developmental areas and geographic location. The charac¬teristics of 152 patients with nephrotic syndrome (NS) admitted to Dicle University School of Medicine between 2001 and 2007 were retrospectively analyzed. Of 152 patients 76 (50%) was female and 76 (50%) was male. The mean age of patients was 36.30 ± 16.5 years. 106 patients (69.7%) had a histologic diagnosis. The frequencies of primary glomerulonephritis were as followed: mem¬branous GN (MGN) 28%, membranoproliferative GN (MPGN) 24% and focal segmental glomerulosclerosis (FSGS) 22.7%. In conclu¬sion MGN was the most common primer GN type in biopsies per¬formed with an NS indication in our region. In our study, MPGN, a decreasing GN type in developed countries, is still common in our region but has a trend to decrease.
Abstract (Original Language): 
Glomerülonefritlerin (GN) sıklıklarındaki dağılım coğrafi bölge ve gelişmişlik derecesine göre değişebilmektedir. 2001-2007 döneminde Dicle Üniversitesi Tıp Fakültesi Nefroloji bölümüne başvuran 152 nefrotik sendromlu (NS) hasta geriye dönük olarak incelendi. 152 hastanın 76'sı (%50) kadın, 76'sı (%50) erkekti. Yaş ortalamaları 36.30 ± 16.5 olarak bulundu. Hastalardan 106'sının (%69.7) doku tanısına ulaşıldı. Primer GN'li hastaların dağılımı; membranöz GN (MGN) %28, membranoproliferatif GN (MPGN) %24, fokal segmental glomerüloskleroz (FSGS) %22.7 ile en sık tanı alan GN'lerdi. Sonuç olarak NS tanısı ile yapılan biyopsilerde en sık primer GN'nin MGN olduğu tespit edildi. MPGN gelişmiş ülkelerde azalmakta, bölgemizde de azalmaklabirlikte hâlâ yay¬gınlığını korumaktadır.

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