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KLİĞİNİMİZDE RENAL TRANSPLANTASYONDA UYGULANAN VİRALPROFİLAKSİNİN DEĞERLENDİRİLMESİ

EVALUATION OF ANTI-VIRAL PROPHYLAXIS FOLLOWING RENAL TRANSPLANTATION

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 1994
Author Name
Abstract (2. Language): 
Infections with Cytomegalovirus (CMV) and other herpes viruses are still an important source of morbidity and mortality in renal transplant recipients and necessitate prophylaxis. 47 patients 25 live related and 22 cadaveric renal transplant recipients were adminis- tered prophylaxis with acyclovir for 6 months and 25 gr immunoglobulin postop. Patients diagnosed as infected with CMV by serological method were followed up for 10.1 ±5.4 months. 21% of cases had CMV disease, 38% had CMV infection and in 17% Herpeas Simplex infection was diagnosed. Tliere were no of loss of patient graft function due to Herpes virus infection.
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Abstract (Original Language): 
Renal transplant alıcılarında CMV (Cytomegalovirus) ve diğer Herpes vimslar halen önemli mortalite ve morbidite nedenidir veprofılaksi gerektirmektedir. 25i canlı, 22si kadaverik donörden transplantasyon yapılan 47olgııluk serimizde 6 ay süre ile acyclovir ve im-münglobülin 25 gr postop proflaksisi uygulandı. Sero-lojik yöntem kullanılarak CMV tanısı konan olgular 10.1±5.4 ay takip edildi. Olguların % 21'inde CMV hastalığı, % 38'inde CMV infeksiyonu, % 17'sinde Herpes simpleks saptandı. Zona zoster hiçbir olguda görülmedi. Herpes viruslar nedeniyle greft ve hasta kaybımız, olmadı.
FULL TEXT (PDF): 
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  • 2
76-80
  • Turkish

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