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HEMODİYALİZ HASTALARINDA SERUM LIPOPROTEIN (a) DÜZEYİ

SERUM LIPOPROTEIN (a) LEVELS IN HEMODIALYSIS PATIENTS

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Abstract (2. Language): 
İn our hemodialysis center, serum Lipoprotein (a) {Lp(a)j, Apoprotein Ai (ApoAi) and Apoprotein B (Apo B) levels were examined in 50 patients and 50 healthy controls. Of the parameters investigated by means of the nefelometer method Lp (a) was found to be high in 38% of hemodialysis patient (18 cases) and 26% of the control group (13 cases). However, there was no statistically significant difference. Serum Apo Al and Apo B levels were significantly lower in patients compared with the control group (p<0.0001). Consequently, it may be said that determination ofLp (a) level, one of the atheronegic risk indicators, may produce useful results in clinical practice.
Abstract (Original Language): 
Hemodiyaliz, mericez.imiz.deki 50 hasta ile 50 sağlıklı kişide serum lipoprotein (a) {Lp(a)}, Apoprotein Al (ApoAl) ve Apoprotein B (Apo B) düzeylerine bakıldı. Nefelometre yöntemi ile araştırılan parametrelerden Lp (a), hemodiyaliz, hasta grubunun %38'inde (18 olgu), kontrol grubunun %26' sında (13 olgu) yüksek bulundu. Fakat istatistiki yönden anlamlı fark yoktu. Serum Apo Al ve Apo B düzeyleri ise hasta grubunda kontrol grubuna göre anlamlı olarak düşüktü (p<0.0001). Sonuç olarak aterojenik risk göstergelerinden olan LP(a) düzeyinin saptanmasının, klinik uygulamada yararlı sonuçlar sağlayabileceği söylenebilir.
FULL TEXT (PDF): 
37-39

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