You are here

AKUT BÖBREK YETERSİZLİĞİNDE KOMPLİKASYONLAR VE MORTALİTE

COMPLICATIONS AND MORTALITY RATE IN ACUTE RENAL FAILURE

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
In this retrospective study we evaluated 64 patients with acute renalfailure (ARF) for age, sex, etiology, renal failure index (RFI), fractional excretion of sodium (FENa), blood urea nitrogen (BUN)\ creatinine, the highest BUN value, rate of daily BUN increase in the pretreatment period; total protein, albumin levels in the pre and 15 th day of posttreatment period; du¬ration of oliguria and polyuria, complications, need for dialysis and mortality rate. The complications we¬re observed in 37 patients (50 %). Mortality rate was found to be 17.2 % In comparison of living and died groups, the mean age, RFI, FENa, rate of daily BUN increase, the mean duration of oliguria and need for dialysis in the group of the died patients were higher than that of the group of the living patients, whe.reas total protein and albumin levels (15th. posttreatment day), the mean duration of polyuria were lower. It was concluded that the factors which affect on the mortality rate include etiology, age, RFI, FENa, the rate of daily BUN increase, durations of oliguria and polyuria, if positive nitrogen balance ensures or not, and complications
Abstract (Original Language): 
Bu retrospektif çalışmada, akut böbrek yetersizliği (ABY) olan 64 hasta yaş, cins, etyoloji, tedavi öncesi renal yetersizlik indeksi (RYİ), fraksiyone sodyum eks-kresyonu (FENa), kan üre azotu (BUN), kreatinin, en yüksek BUN değeri, günlük BUN yükselme hızı, total protein, albumin; tedavinin 15. günü total protein, al¬bumin değerleri; oligüri ve poliüri süresi, komplikas-yon, diyaliz ihtiyacı ve mortalite hızı açısından de¬ğerlendirildi. Toplam 37 hastada (% 50) komplikas-yon görüldü. Mortalite hızı % 17.2 idi. Yaşayan ve ölen hasta grupları karşılaştırıldığında ölen hasta grubunda yaşayan hasta grubuna göre yaş ortalama-ası, RYİ, FENa, günlük BUN artışı, ortalama oligüri süresi ve diyaliz ihtiyacının anlamlı olarak daha yük¬sek olduğu, tedavinin 15. günü serum total protein al¬bumin seviyeleri, ortalama poliüri süresinin ise daha düşük olduğu saptandı. Sonuç olarak mortalite üzeri¬ne etkili faktörlerin etyoloji, yaş, RYİ, FENa, günlük BUN artış hızı, oligüri ve poliüri süresi, diyaliz ihti¬yacı, pozitif nitrojen dengesinin temin edilip edilmedi¬ği ve komplikasyonlar olduğu sonucuna varıldı.
FULL TEXT (PDF): 
106-110

REFERENCES

References: 

1. Anderson RJ, Schrier RW. Acute Renal Failure. In Bra-unwald E, Isselbacher KJ, Pedersdof RG: Harrison's
Principles of Internal Medicine. 2 (Eleventh ed). Me Graw-Hill Book Co, New York 1987; 1149-1155.
2. Grantham JJ. Acute Renal Failure. In: Cecil's Textbook of Medicine (17th ed.).WB Saunders, Philadelphia
1985, pp 544-549.
3. Yiicesoy
M
, Başar E, Hasanoğlu E. Türkiye'de Akut Böbrek Yetmezliğinin Etyolojisi Değişiyor mu ? Türkiye Klinikleri Tıp Bilimleri Araştırma Dergisi 1990; 8: 543-548.
4. Brezis M, Rosen S, Epstein HF. Acute Renal Failure.
The Kidney 735-799, 1984.
5. Thompson M. Use of essential Amino Acid/Dextrose Solutions in the Nurtritional Management of Patients of Patients With Acute Renal Failure. Drug Intel! Clin
Pharm 1985; 19: 106-111.
6. Feinstein EL. Nutrition in Acute Renal Failure. Adv Exp
Med Biol 1987; 212: 297-301.
7. Finn WF. Diagnosis and Management of Acute Tubular
Necrosis. Med Clin North Am 1990; 74: 873-891.
8. Schrier RW, Arnold PE, Van Putten VJ. Cellular Calci¬um in Ischemic Acute Renal Failure: Roje of Calcium
Entry Blockers. Kidney Int 1987; 32: 313.
9. Conger JD, Folk SA, Yuan BH, Schrier RW. Atrial nat-
riuretic peptide and dopamine in a rat model of ischemic
acute renal failure. Kidney Int 1989; 35: 1126-1132.
10. Lidner A. Synergism of dopamine and furosemide and diuretic resistant oliguric acute renal failure. Nephron
1983; 33: 121-126.
11. Sacks SH, Ledinghan GJ. Management of Acute Renal
Failure. Hospital Update 1986; 187-204.
12. Ter Wee PM, Geerlings W, Rosman JB, Stuiter WJ,
Gess SV, Donker JM. Testing Renal Reserve Filtration Capacity With an Amino Acid Solution. Nephron 1985;
41: 193-199.
13. Graf
H
, Stummuoll HK, Luger A, Prager R. Effect of Amino Acid Infusion on Glomerular Filtration Rate. N
Eng J Med 1983; 308: 159-160. '
14. Castellino P, Coda B, DeFronzo RA. The Effect of Int¬ravenous Amino Acid Infusion on Renal Hemodyna-
mics in Man. Kidney Int 27: 243, 1985.
15. Ruilope LM, Rodicio J, Robles RG, et al. Influence of a low sodium diet on the renal response to amino acid in¬fusions in humans. Kidney Int 1987; 31: 992-999.
16. Castellino P, Coda B, DeFronza RA. Effect of amino acid infusion on renal hemodynamics in humans. Am J Physiol 1986; 251: F132-F140.
17. Hirschberg RR, Zipser RD, Slomewitz LA, Kopple JD. Glucagon and prostaglandins are mediators of amino acid-induced rise in renal hemodynamics. Kidney Int
1988; 33: 1147-155.
18.
Te
r We PM, Rosman JB, Geest SV, Sluiter WJ, Donker JM. Renal Hemodynamics During Separate and Combi¬ned Infusion of Amino Acids and Dopamine. Kidney Int
1986; 29: 870-874.
19. Abel RM. Nutritional Support in the Patients With Acu¬te Renal Failure. J Am Col N 1983; 2: 33-44.
20. Abel RM, Beck GH, Abbott WM, Ryan JA, Barnet GO,
Fischer JE. Improved survival from Acute Renal Failure After Treatment with Intravenous Essential L-Amino
Acids and Glucose. N Engl J Med 1973; 288: 695-699.
21. Fischer JE. Nutritional Support: NITA Vol 4, Novem¬ber/December 1981.
109
22. McClave S, Short AF, Mattingly DB, Fitzgerald PD. Total Parenteral Nutrition. Postgrad Med 1990; 88: 1.
23. Aparicio M, vincendeau P, Combe L, et al. Improve¬ment of leucocytic Na-K pump activity in uremic pati¬ents on low protein diet. Kidney Int 1991; 40: 238-242.
24. Spiegel DM, Ullian ME, Zerbe GO, Berl T. Determi¬nants of Survival and Recovery in Acute Renal Failure Patients Dialyzed in Intensive - Care Units. Am J Nephrol 1991; 11: 44-47.
25. Min Baek S, Makaboli GG, Brayn-Brown LW, Kusek J, Shoemaker WL. The Influence of Parenteral Nutrition on the Course of Acute Renal Failure. Surgery Gynecol Obstet 1975; 141: 405-408.
26. Gluy UM, Turney JH. Post-traumatic acute renal failure, 1959-1988. Clin Nephrol 1990; 34: 79-83.

Thank you for copying data from http://www.arastirmax.com