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REAKTIF OKSİJEN PARTIKULLERI VE ANTÎOKSÎDAN SAVUNMA

REACTIVE OXYGEN PARTICLES AND ANTIOXIDANT DEFENCE

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 1997

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
Free radicals are molecules which contain one or more unpaired electrons. These molecules are highly reactive and tend to initiate chain reactions with other molecules also called oxidants or reactive oxygen particles (ROP). Molecules which protect proteins, lipids, carbohydrates and nucleic acids against free radicals are called antioxidants and so this reaction is called antioxidant defence system. Increased oxidants are antagonized by antioxidants in human body. In this review, ROP and antioxidant defences will be discussed.
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Abstract (Original Language): 
Serbest radikal, atomik yada moleküler yapılarda çiftlenmemiş bir veya daha fazla tek elektron taşıyan moleküllere verilen isimdir. Başka moleküller ile çok kolayca elektron alışverişine giren bu moleküllere oksidan moleküller veya reaktif oksijen partikülleri de denmektedir. Canlı hücrelerde bulunan protein, lipid, karbohidrat ve DNA gibi okside olabilecek maddelerin oksidasyonunu önleyen veya geciktirebilen maddelere de antioksidanlar ve bu olaya antioksidan savunma denir. Belirli bir düzeye kadar olabilen oksidan molekül artışı yine vücutta daima belirli bir düzeyde bulunan doğal antioksidanlar tarafından etkisiz. hale getirilmektedir. Bu makalede reaktif oksijen partikülleri ve antioksidan savunma kavramları hakkında genel bir değerlendirme sunulacaktır.
FULL TEXT (PDF): 
PDF icon pdf_tndt_176.pdf
  • 3-4
92-95
  • Turkish

REFERENCES

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