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BÖBREK TRANSPLANTASYONU YAPILMIŞ ÎKÎ OLGUDA POST TRANSPLANT LENFOPROLÎFERATÎF HASTALIK

POST TRANSPLANT LYMHOPROLIFERATIVE DISORDERS IN RENAL ALLOGRAFT PATIENTS

Journal Name:

  • Türk Nefroloji, Diyaliz ve Transplantasyon Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

Author NameUniversity of AuthorFaculty of Author
Abstract (2. Language): 
After organ transplantation, different clinical and histopathological forms of post transplant lymphoproliferative diseases (PTLDs) related to imniunsiipression are observed. Post transplant lymphomas within the PTLDs have different propertiescompared to nonimmunosupressed. In PTLDs, organ involvement is frequent, histology is often high-grade and the prognosis is bad. In this study we present clinical and histopathological properties of two patients who have developed PTLD-B cell lymphoblastic lymphoma four years after renal transplantation. One of the patients have bladder lymphoma and there is no reported case of bladder PTLD. Because PTLD's are rare fatal complications, both are presented.
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Abstract (Original Language): 
Organ transplantasyonlarının ardından immunsüpresyonla ilişkili olarak farklı klinik ve histolojik şekillerde post transplant lenfoproliferatif hastalıklar (PTLH) görülmektedir. PTLH grubunda görülen lenfomalar immunsüpresyon almayan olgularda gördüklerimizden farklı özellikler taşımaktadır. Organ tutulumu sıktır, yüksek derecelidir veprognozları kötüdür. Bu çalışmada böbrek transplantasyonu yapıldıktan yaklaşık dört sene sonra PTLH- B hücreli lenfoblastik lenfoma saptanan iki olgunun klinik ve patolojik özellikleri sunulmuştur. Olgulardan biri mesane lenfoması olup literatürde mesanede yayınlanmış PTLH olgusu bulunamamıştır. PTLH'ların nadir ancak ölümcül komplikasy onlar olmaları nedeniyle olgular sunulmuştur.
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  • 1
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  • Turkish

REFERENCES

References: 

1. Ferry JA, Harris LA. Pathology of posttranplant lymphoproliterative disorders. In Solez K, Racusen LC, Billingham ME (ed), Solid organ transplant rejection. Mechanisms, pathology and diagnosis. Marcel Dekker Inc. New York 1996, pp 277-301.
2. Medeiros LJ. Post-transplant lymphoproliferative disorders. In Jaffe ES (ed). Surgical pathology of the lymph nodes and related organs. İkinci baskı. WB Saunders Company Philadelphia. 1995, pp. 325-330.
3. Swerdlow SH. Classification of the posttransplant lymphoproliferative disorders: From the past to the present. Seminars in Diagnostic Pathology 1997; 14: 2¬7.
4. Nalesnik MA, Jaffe R, Starzl TE, Demetris AJ, Porter
K, Burnham JA, Makowka L, Ho M, Locker J. The pathology of posttransplant lymphoproliferative disorders occuring in the setting of cyclosporine A-prednisone immunosupression. American Journal of
Pathology 1988; 133: 173-192.
5. Harris NL.Ferry JA, Swerdlow SH. Post transplant lymphoproliferative disorders. Summary of society for
hematopathology workshop. Seminars in Diagnostic Pathology 1997; 14:8-14.
6. Demircin G, Öner A. Posttranplant lenfoproliferatif hastalık. Türk Nefroloji Diyaliz ve Transplantasyon
Dergisi 1998; 1:40-43.
7. Sayegh MH, Carpenter CB, Eisen HJ.
Lymphoproliferative disorders following solid organ
transplantation. UpToDate CD-ROM. Vol. 7, No. 3. 1999
8. Goral S, Felgar R, Shappell S. Post transplantation lymphoproliferative disorder in a renal allograft recipient. American Journal of Kidney Diseases 1997;
30(2): 301-307.
9. Randhawa P, Demetris AJ, Pietrzak B, Nalesnik M. Histopathology of renal posttransplant lymphoproliferation: comparison with rejection using
the Banff schema. Am J Kidney Dis. 1996 ; 28: 578-84.
10. Penn I, Porat G. Central nervous system lymhomas in organ allograft recepients. Transplantation 1995; 59: 240-244.
11. Young RH. Unusual variants of primary bladder carcinoma and secondary tumors of the bladder. Young RH (ed), Pathology of the urinary bladder. Churchill
Livingstone New York. 1989, pp 103-138.
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