Tip 2 Diyabet Tedavisinde Son Gelişmeler

Nurver Turfaner

RECENT ADVANCES IN THE MANAGEMENT OF TYPE 2 DIABETES MELLITUS

Journal Name:

Türkiye Aile Hekimliği Dergisi

Publication Year:

2007

Key Words:

Keywords (Original Language):

Author Name	University of Author	Faculty of Author
Nurver Turfaner	İstanbul Üniversitesi	Cerrahpaşa Tıp Fakültesi

Abstract (2. Language):

Choices have increased in the treatment of type 2 diabetes with new antidiabetics and insulins. According to the new American Diabetes Association criteria, the goal in fasting glucose is <100mg/dl and 2 hours after meals it is <140mg/dl. The drugs which can be used for oral therapy in Type 2 diabetes are sul-phonilureas, non-sulphonilurea secretagogs, biguanides, alpha-glucosidase inhibitors and thiazolidinedions. The situations where insulin therapy is required are severe hypoglycemia, impaired glucose control with maximum dose of oral therapy, intervening dis¬eases (myocardial infarction, infection) or operation, pregnancy, kidney disease, liver disease, allergy or intolerance to oral antidia-betics. Mixed insulins (NPH, Human analog), rapid acting insulin analogues (Lispro, aspart) and basal insulin analogues (insulin glargine) can also be used.

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Abstract (Original Language):

Son yıllarda çıkan yeni oral antidiyabetikler ve insülinlerle tip 2 diyabet tedavisinde seçenekler çoğalmıştır. Amerikan Diyabet Der-neği'nin yeni ölçütlerine göre hedefler açlık kan şekeri <100mg/dl, yemekten sonra 2.saatte <140mg/dl olarak belirlenmiştir. Tip 2 diyabetin oral tedavisinde kullanılan ilaçlar sülfonilü-reler, sulfonilüre olmayan insülin sekretagoglar, biguanidler, alfa-glikozidaz inhibitörleri ve tiazolidinedionlardır. insülin tedavisi ge¬rektiren durumlar ise ağır hipoglisemi, oral ilaçların maksimum dozlarını alırken bozuk glikoz kontrolü, araya giren hastalıklar (miyokard infarktüsü, enfeksiyon) veya operasyon, gebelik, böbrek hastalığı, karaciğer hastalığı, oral antidiyabetiklere intolerans veya alerjidir. Karışık insülinler (NPH, human analog), çabuk etkili insülin analogları (lispro insülin, aspart insülin) ve bazal insülin analogları (insülin glargin) kullanılabilir.

FULL TEXT (PDF):

arastrmx_116859_11_pp_43-47.pdf

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43-47

Turkish

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Tip 2 Diyabet Tedavisinde Son Gelişmeler

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Keywords (Original Language):

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