You are here

İstanbul Kartal bölgesinde okul öncesi çocuklarda asemptomatik A grubu beta hemolitik streptokok taşıyıcılığı

Asymptomatic carriage of group A beta-hemolytic streptococcus among preschool children in Kartal, Istanbul

Journal Name:

Publication Year:

DOI: 
doi:10.2399/tahd.08.203
Abstract (2. Language): 
Objective: Group A beta-hemolytic streptococcus (GABHS) is the most common bacterial cause o f acute pharyngitis in children a nd may cause serious complications such as acute rheumatic fever and acute glomerulonephritis. The objective of this study was t o determine the rate of carriage for GABHS among asymptomatic, preschool children w h o apply t o Dr. Lütfi Kırdar Teaching a nd Research Hospital - Family Medicine Outpatient Clinic in Istanbul. Methods: One hundred and fifty children between 3 t o 6 years of age, enrolled in t h e family medicine outpatient clinic f o r other reasons than sore t h r o a t , f r om January t o March 2008, were ran¬ domly and prospectively included in the study. Following history taking and physical examination, swabs of the oropharynx were taken for bacteriological culture and identification. Blood samples were collected and antibodies t o streptolysin O were dedected by latex agglutination tests (ASO). Results: Positive throat cultures t o GABHS were f o u n d in 18 o f 128 patients ( 1 4 . 0 6 % ) and 8 of these ( 4 4 . 4 4 % ) had elevated ASO titers w i t h o u t any proven findings of streptococcal infection. Conclusions: Previous studies demonstrated that the prevalence of GABHS in healthy preschool children was between 2 t o 2 5 . 9 % . Pharyngeal carriage of GABHS of our sample was f o u n d similar w i t h results obtained in t h e western parts o f Turkey.
Abstract (Original Language): 
Amaç: A grubu beta hemolitik streptokok (AGBHS) çocukta akut bakteriye! farenjitin en sık rastlanan etkenidir ve akut romatizmal ateş, akut glomerülonefrit gibi ciddi komplikasyonlara yol açabilir. Bu çalışmanın amacı istanbul Kartal Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi Aile Hekimliği Polikliniği'ne başvuran okul öncesi çocuklarda AGBHS taşıyıcılığı oranını belirlemektir. Yöntem: Ocak-Mart 2008 tarihleri arasında aile hekimliği polikliniğimize boğaz ağrısı dışındaki nedenlerle başvuran üç ila altı yaş arası ardışık 150 çocuk hasta randomize şekilde çalışmaya dâhil edildi. Anamnez ve fizik muayene sonrası bakteri kültürü ve ta¬ nımlama için boğaz sürüntüsü ile antistreptolizin O (ASO) testi için kan örneği alındı. Bulgular: incelenen 128 hastanın 18'inin ( % 1 4 . 0 6 ) boğaz kültürü, AGBHS pozitifti; kültürü pozitif olanların 8'inde ise ( % 4 4 . 4 4 ) herhangi bir s t r e p t o k o k enfeksiyonu bulgusu olmaksızın ASO yük¬ selmesi saptandı. Sonuç: Daha önceki çalışmalarda, sağlıklı okul öncesi çocuklarda % 2 - 2 5 . 9 oranlarında faringeal AGBHS taşıyıcılığı bulunmuştu, çalışmamızdaki AGBHS taşıyıcılığı Türkiye'nin batı yörelerindeki so¬ nuçlarla uyumludur.
203-206

REFERENCES

References: 

Olympia RP, Khine H, Avner JR. Effectiveness of oral dexamethasone in the treatment of moderate to severe pharyngitis in children. Arch Pediatr Adolesc Med 2005; 159: 278-82.
2. Zwart S, Rovers MM, de Melker RA, Hoes AW. Penicillin for acute sore throat in children: randomised, double blind trial. BMJ 2003; 327: 1324.
3. Pichichero ME. Group A streptococcal tonsillopharyngitis: cost-effective diagnosis and treatment. Ann EmergMed 1995; 25: 390-403.
4. Pichichero ME. Group A beta-hemolytic streptococcal infections. Pediatr Rev 1998; 19: 291-302.
5. Hayes CS, Williamson H Jr. Management of group A beta-hemolytic streptococcal pharyngitis. Am Fam Physician 2001; 63: 1557-65.
6. Weber DJ, Rutala WA, Denny FW. Management of healthcare workers with pharyngitis or suspected streptococcal infections. Infect Control Hosp
Epidemiol1996; 17: 753-61.
7. 2000, Red Book Report of the Committee on Infectious Diseases. Ed. Pickering LK 25. baskı. Elk Grove Village, American Academy of
Pediatrics, 2000; 526-36.
8. Erol N, Türkmen A, Özgüner A, Yavrucu S. Acute rheumatic fever: Retrospective evaluation of 60 cases. J Kartal TR 2002; 13: 165-9.
9. Bisno AL, Gerber MA, Gwaltney JM, Kaplan EL, Schwartz RH.
Diagnosis and management of group A streptococcal pharyngitis: a prac¬tice guideline. Infectious Diseases Society of America. Clin Infect Dis
1997; 25: 574-83.
10. Bisno AL, Gerber MA, Gwaltney JM, Kaplan EL, Schwartz RH. Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America. Clin Infect Dis 2002;
15: 113-25.
11. Ozturk CE, Yavuz T, Kaya D, Yucel M. The rate of asymptomatic throat carriage of group A streptococcus in school children and associated ASO titers in Duzce, Turkey. Jpn J Infect Dis 2004; 57: 271-2.
12. Danchin MH, Rogers S, Kelpie L, Selvaraj G, Curtis N, Carlin JB, Nolan TM, Carapetis JR. Burden of acute sore throat and group A streptococcal pharyngitis in school-aged children and their families in Australia.
Pediatrics2007; 120: 950-7.
13. Prince A. Infectious diseases. Nelson Essentials of Pediatrics'de. Ed. Behrman RE, Kliegmen RM. 3. baskı. Philadelphia, W.B. Saunders
Company, 1998; 373-5.
14. Öneş Ü, Yalçın I, Salman N. Bakteriyel infeksiyonlar. Pediatri'de. Ed. Neyzi O, Ertuğrul TY. İstanbul, Nobel Tıp Kitabevi, 1989; 589-93.
15. Vieira FM, Figueiredo CR, Soares MC, Weckx LY, Santos O, Magalhaes G, Orlandi P, Weckx LL, Pignatari S. Prevalence of streptococcus pyo-genes as an oropharynx colonizer in children attending daycare: a com¬parative study of different regions in Brazil. Rev Bras Otorrinolaringol (Eng Ed.) 2006; 72: 587-91.
16.
Tun
ç B, Yorgancıgil B, Aydemir M, Doğru H, Demirci M. Isparta ilin¬deki üç ilkokulda beta hemolitik streptokok görülme sıklığı. SDÜ Tıp Fakültesi Dergisi 1995; 2(4): 33-7.
17.
Metinta
ş S, Kalyoncu C, Etiz S, Kiraz N, Ünsal A. Çifteler ilçesi ilkokul çocuklarında A grubu beta hemolitik streptokok (GABHS) prevalansı. Anadolu Tıp Dergisi 1991; 13: 17-21.
18. Pacifico L, Scopetti F, Ranucci A, Pataracchia M, Savignoni F, Chiesa C. Comparative efficacy and safety of 3-day azithromycin and 10-day peni¬cillin V treatment of group A beta-hemolytic streptococcal pharyngitis in children. Antimicrob Agents Chemother 1996; 40: 1005-8.

Thank you for copying data from http://www.arastirmax.com