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Pubertal dönemde meme problemleri

Breast anomalies in pubertal period

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Abstract (2. Language): 
Most of constitutional anomalies of breast tissues, other than tumoral diseases in adulthood, are seen in pubertal and prepu-bertal period . Surgical therapies are important as either first and single step or last resort after mostly failed medical therapy in the treatment of breast anomalies which could be classified as hyper-plastic, hypoplastic, and deformational. Satisfying results have fre¬quently been obtained by surgery alone in the treatment of constitutional breast anomalies. In gynecomastia, one of the most encountered hyperplastic breast anomalies, which has marked hormonal interactions and etiologic factors, none of the suggest¬ed medical therapies has been approved yet. Surgical therapies become the main method of treatment for gynecomastia when medical therapy fails or in advanced stage of gynecomastia. In this article, pubertal breast problems were reviewed by a surgeon's view.
Abstract (Original Language): 
Memenin erişkin dönemdeki tümöral hastalıkları dışında, birçok gelişim anomalileri ve hastalıkları pubertal ve prepubertal dönemleri ilgilendirir. Temel olarak hiperplastik, hipoplastik ve deformasyonel olarak sınıflandırılabilen meme anomalilerinin tedavisinde cerrahî girişimler ya ilk ve tek seçenek ya da çoğu kez olduğu gibi medikal önlemlerin yetersiz kaldığında son çare olarak önemlidirler. Memenin yapısal anomalilerinde tek başına cerrahi işlemlerle çok iyi sonuçlar elde edilmektedir. Jinekomasti hiperplastik meme anomalileri içinde en sık karşılaşılanlardan birisidir. Hormonal etkileşimlerin fazla ve eti-yolojik nedenlerin çok çeşitli olduğu jinekomasti gibi hastalıklarda, ilaç tedavisi önerileri varsa da bu öneriler henüz tam olarak onaylan¬mamıştır. ilaç tedavisinin yetersiz olduğu veya ileri evre jinekomasti-lerde cerrahi girişimler yine asıl tedavi şeklini oluşturmaktadır. Bu derleme yazısında, pubertal dönemdeki meme problemleri bir cer¬rah gözüyle değerlendirilmiştir.
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REFERENCES

References: 

1. Sadove AM, van Aalst JA. Congenital and acquired pediatric breast anomalies: a review of 20 years' experience. Plast Reconstr Surg 2005;115:1039-50.
2. Greydanus DE, Matytsina L, Gains M. Breast disorders in children and adolescents. Prim Care 2006;33:455-502.
3. van Aalst JA, Sadove AM. Treatment of pediatric breast problems. Clin Plast Surg 2005;32:65-78.
4. Li YF, Lv MH, Chen LF, Wu YF. Giant lipoma of the breast: a case report and review of the literature. Clin Breast Cancer 2011;11:420-2.
5. Zambacos GJ, Mandrekas AD. The incidence of tuberous breast deformity in asymmetric and symmetric mammaplasty patients. Plast Reconstr Surg
2006;118:1667.
6. Pryor LS, Lehman JA Jr, Workman MC. Disorders of the female breast in the pediatric age group. Plast Reconstr Surg 2009;124:50e-60e.
7. Kahan S, DeAntonis KO. Gynecomastia. In: Pediatrics. Philadelphia: Lippincott Williams & Wilkins; 2003. p. 78.
8. Mathes SJ, Seyfer AE, Miranda EP. Congenital anomaliesof the chest wall. Mathes Plastic Surgery. In: Mathes SJ, editor. 2nd ed. Vol. 6. Philadelphia:
WB Saunders; 2006. p. 457-537.
9. Maidment SL. Question 2. Which medications effectively reduce pubertal gynaecomastia? Arch Dis Child 2010;95:237-9.
10. Güvenç H, Yurdakök M, Kinik E, Büyükgebiz A. The incidence of puber-tal gynecomastia in boys living in the Ankara region. Turk J Pediatr 1989;
31:123-6.
11. Abaci A, Buyukgebiz A. Gynecomastia: review. Pediatr Endocrinol Rev2007;
5:489-99.
12. Neyzi O, Alp H, Yalcindag A, Yakacikli S, Orphon A. Sexual maturation in Turkish boys. Ann Hum Biol1975;2:251-9.
13. Daniels IR, Layer GT. How should gynaecomastia be managed? ANZ J
Surg2003;73:213-6.
14. Matsumoto AM, Bremner WJ. Testicular disorders. In: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, editors. Williams Textbook of Endocrinology. 12th ed. Philadelphia: Saunders-Elsevier; 2011:717-771.
15. Braunstein GD. Gynecomastia. N Engl J Med1993;328:490-5.
16. Narula HS, Carlson HE. Gynecomastia. Endocrinol Metab Clin North Am
2007;36:497-519.
17. Bembo SA, Carlson HE. Gynecomastia: its features, and when and how to
treat it. Cleve Clin J Med2004;71:511-7.
18. Cinaz P. Pubertal Jinekomasti. Türk Pediatri Arşivi 2011;46:82-4.
Türkiye Aile Hekimliği Dergisi | Turkish Journal of Family Practice | Cilt 16 | Ek / Suppl | 2012
S29
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
Large DM, Anderson DC. Twenty-four hour profiles of circulating andro-gens and oestrogens in male puberty with and without gynaecomastia. Clin Endocrinol (Oxf 1979;11:505-21.
Ma NS, Geffner ME. Gynecomastia in prepubertal and pubertal men. Curr
Opin Pediatr2008;20:465-70.
Kumanov P, Deepinder F, Robeva R, Tomova A, Li J, Agarwal A. Relationship of adolescent gynecomastia with varicocele and somatometric parameters: a cross-sectional study in 6200 healthy boys. J Adolesc Health
2007;41:126-31.
Georgiadis E, Papandreou L, Evangelopoulou C, Aliferis ve ark. Incidence of gynaecomastia in 954 young males and its relationship to somatometric parameters. Ann Hum Biol 1994;21:579-87.
Niewoehner CB, Nuttal FQ. Gynecomastia in a hospitalized male popula¬tion. Am J Med 1984;77:633-8.
Sher ES, Migeon CJ, Berkovitz GD. Evaluation of boys with marked breast development at puberty. Clin Pediatr (Phila) 1998;37:367-71.
Bayraktaroğlu T, Kargı E, Yeşilli Ç, Numanoğlu G, Borazan A, Üstündağ Y. Erkekde kısa süreli marihuana (esrar) kullanımının beklenmedik etkileri: Jinekomasti ve oligoastenospermi. Bağımlılık Dergisi 2004;5:35-9. Meara JG, Kolker A, Bartlett G, Theile R, Mutimer K, Holmes AD. Tuberous breast deformity: principles and practice. Ann Plast Surg2000;45: 607-11. Tazi MF, Mellas S, El Fassi MJ, Farih MH. Leydig cell hyperplasia revealed by gynecomastia. Rev Urol 2008;10:164-7.
Kayemba-Kays S, Fromont-Hankard G, Lettelier G, Gabriel S, Levard G. Leydig cell tumour revealed by bilateral gynecomastia in a 15-year-old ado¬lescent: a patient report. J Pediatr Endocrinol Metab 2010;23:1195-9. Jurewicz J, Hanke W. Exposure to phthalates: reproductive outcome and children health. A review of epidemiological studies. Int J Occup Med
Environ Health 2011;24:115-41.
Durmaz E, Özmert EN ve ark. Plasma phthalate levels in pubertal gyneco-mastia. Pediatrics 2010;125:e122-9.
Den Hond E, Dhooge W, Bruckers L, ve ark. Internal exposure to pollu¬tants and sexual maturation in Flemish adolescents. J Expo Sci Environ
Epidemiol2011;21:224-33.
Gavaler JS. Alcoholic beverages as a source of estrogens. Alcohol Health Res World 1998;22:220-7.
Dundar B, Dundar N, Erci T, Bober E, Büyükgebiz A. Leptin levels in boys with pubertal gynecomastia. J Pediatr Endocrinol Metab 2005;18:929-34. Ersöz H, Onde ME, Terekeci H, Kurtoglu S, Tor H. Causes of gynaeco-mastia in young adult males and factors associated with idiopathic gynaeco-
mastia. Int J Androl2002;25:312-6.
Allee MR. Gynecomastia. http://emedicine.medscape.com/article/120858-overview 13/11/2011 tarihinde erişilmiştir.
Joffe A. Gynecomastia. In: Neinstein LS, editor. 5th ed. Adolescent Health Care A practical Guide. Philadelphia: Wolters Kluwer/Lippincott Williams
& Wilkins; 2008. p. 180-4.
Isakov R. Gynecomastia. In: Siemionow MZ, Eisenmann-Klein M, edi¬tors. Plastic and Reconstructive Surgery. New York: Springer; 2010. p.
459-465.
Pensler JM. Plastic surgery for gynecomastia, http://emedicine.med- scape.com/article/1273437 -overview 13/11/2011 tarihinde erişilmiştir.
40.
41.
42.
44.
45.
46.
47.
39. Wilson G, Mooradian A, Aleandraki I, Samrai G. Endocrinology. In: Rakel RE, Rakel D, editors. Textbook of Family Medicine. 8th ed.Philadelphia:
Saunders-Elsevier; 2011. p. 789-801.
Khan HN, Rampaul R, Blamey RW. Management of physiological gynae-comastia with tamoxifen. Breast2004;13:61-5.
Derman O, Kanbur N, Kilic I, Kutluk T. Long-term follow-up of tamox-ifen treatment in adolescents with gynecomastia. J Pediatr Endocrinol Metab
2008;21:449-54.
LeRoith D, Sobel R, Glick SM. The effect of clomiphene citrate on puber-tal gynaecomastia. Acta Endocrinol (Copenh) 1980;95:177-80. 43. Ting AC, Chow LW, Leung YF. Comparison of tamoxifen with danazol in the management of idiopathic gynecomastia. Am Surg2000;66:38-40. Jones DJ, Holt SD, Surtees P, Davison DJ, Coptcoat MJ. A comparison of danazol and placebo in the treatment of adult idiopathic gynaecomastia: results of a prospective study in 55 patients. Ann R Coll Surg Engl1990;72: 296-8. Lawrence SE, Faught KA, Vethamuthu J, Lawson ML. Beneficial effects of raloxifene and tamoxifen in the treatment of pubertal gynecomastia. J
Pediatr2004;145:71-6.
Riepe FG, Baus I, Wiest S, Krone N, Sippell WG, Partsch CJ. Treatment of pubertal gynecomastia with the specific aromatase inhibitor anastrozole.
Horm Res2004;62:113-8
Plourde PV, Reiter EO, Jou HC, ve ark. Safety and efficacy of anastrozole for the treatment of pubertal gynecomastia: a randomized, double-blind,
placebo-controlled trial. J Clin Endocrinol Metab2004;89:4428-33.
48. Mauras N, Bishop K, Merinbaum D, Emeribe U, Agbo F, Lowe E. Pharmacokinetics and pharmacodynamics of anastrozole in pubertal boys with recent-onset gynecomastia. J Clin Endocrinol Metab 2009;94:2975-8.
49. Zachmann M, Eiholzer U, Muritano M, Werder EA, Manella B. Treatment of pubertal gynaecomastia with testolactone. Acta Endocrinol
Suppl (Copenh) 1986;279:218-26.
Stöppler MC. Gynecomastia. http://www.medicinet.comscript/main/art.asp? articlekey=106344 13/11/2011 tarihinde erişilmiştir.
Hoppe IC, Patel PP, Singer-Granick CJ, Granick MS. Virginal mammary hypertrophy: a meta-analysis and treatment algorithm. Plast Reconstr Surg
2011;127:2224-31.
Fiumara L, Gault DT, Nel MR, Lucas DN, Courtauld E. Massive bilater¬al breast reduction in an 11-year-old girl: 24% ablation of body weight. J Plast Reconstr Aesthet Surg2009;62:e263-6.
Baker SB, Burkey BA, Thornton P, LaRossa D. Juvenile gigantomastia: presentation of four cases and review of the literature. Ann Plast Surg 2001;
46:517-25.
Gentimi F, Loupatatzi ACh, Euthimoglou KP, ve ark. Juvenile gigantomas-tia in a 12-year-old girl: a caser eport. Aesthetic Plast Surg2011;35: 414-7. Ellouz M, Benjilani S. Prepubertal gigantomastia treated by mastectomy with an implant. Ann Chir Plast Esthet1990;35:157-9. Cardoso de Castro C, Aboudib JH, Salema R, Valladares B. Massive breast hypertrophy in a young girl. Ann Plast Surg1990;25:497-501.
57. Ağaoğlu G, Ozgür F, Erk Y. Unilateral virginal breast hypertrophy. Ann
Plast Surg2000;45:451-3.
58. Govrin-Yehudain J, Kogan L, Cohen HI, Falik-Zaccai TC. Familial juve¬nile hypertrophy of the breast. J Adolesc Health 2004;35:151-5.

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