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ORAL REHİDRATASYON SOLÜSYONLARININ KULLANIMINDA YENİLİKLER, KOMPOZİSYON VE ETKİNLİK

UPDATE ON COMPOSITION, EFFICIENCY AND USE OF ORAL REHYDRATION SOLUTIONS

Journal Name:

  • Türkiye Aile Hekimliği Dergisi

Publication Year:

  • 2000

Key Words:

Keywords (Original Language):

Author Name
Abstract (2. Language): 
Oral rehydration solutions are used primarily for the prevention and therapy of dehyration.A significant development in recent years has been the discovery that dehyration from acute diarrheas of all etiologies and all age groups can be safely and effectively treated by using a simple oral fluid. Glucose, sodium chloride, trisodium citrate dihydrate and potasyum chlorid e- in a mixture known as oral rehydration salts (ORS) - are dissolved in water to form ORS solution. Given orally, ORS solution is absorbed in the small intestine du¬ring copious diarrhoea, thus replacing the water and electrolytes lost in the faeces. The clinical and scientific rationale is now well established, as are many of the practical issues with respect to its administration and distribution worldwide. Controversy continues , however, as to the ideal composition of these solutions and , in particular as to whether one solution should be recommended for worldwide use or different geographical locations. ORS will continue to be the mainstay of therapy for acute dehydra¬ting diarrhea but work continues to optimize composition and thus efficacy and more importantly, to ensure adequate resources for its continued implementation worldwide, particulary in those parts of the world where the prevalence of diarrheal disease remains high.
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Abstract (Original Language): 
Oral rehidratasyon solüsyonlar ı (ORS) özellikle dehidratasyonunun tedavisi ve önlenmesinde kullanılır. Farklı etiyolojiler ve yaş gruplarında akut ishale bağlı oluşan dehidratasyonun, basit bir sıvı kullanılarak kolay bir yöntemle etkili ve güvenli olarak tedavi edilebileceğinin keşfi, son yıllarda önemi anlaşılan bir gelişmedir. Glükoz, sod¬yum klorid, trisodyum sitrat dihidrat ve potasyum klorid tuzları su¬da çözülerek ORS'nı oluştururlar. Oral olarak verildiğinde ORS bol miktarda diyare olduğunda bile ince bağırsaktan kolayca absorbe edilir. Böylece feçesle atılan su ve elektrolitler geri emilir. Tüm dünyada ORS'nin dağıtım ve uygulanmasıyla ilgili birçok pratik konuda klinik ve bilimsel tavır günümüzde iyi saptanmıştır. Farklı coğrafi bölgeler için uygun olan farklı formulasyonlar olup ol¬madığı veya tüm dünyada kullanılacak tek bir solüsyon önerilip öne-rilemeyeceği ve hidrasyonun sürmesi için modifiye solusyonların kullanılması konusunda görüş birliği yoktur. ORS, dehidratasyon için tedavinin anabileşeni olmayı sürdürmektedir, ancak kompozisyonunu optimize etme çabaları da sürdürülmekte, böylelikle etkinlik ve daha önemlisi dünyada, özellikle ishalli hastalık prevalansının yüksek olduğu ülkelerde, ORS uygulaması için yeni kaynaklar sağlanmaya çalışılmaktadır.
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  • 1-4
27-33
  • Turkish

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