You are here

Olgu Sunumu: Primer Testis Lenfoması

Primary Testicular Lymphoma

Journal Name:

Publication Year:

Keywords (Original Language):

Abstract (2. Language): 
Non-Hodgkin lymphoma of the testis is an uncommon disease. It accounts for 1%- 9% of all testicular neoplasms. Despite this low overall incidence, it is the most common testicular malignancy over the age of 60. Diffuse large B-cell lymphoma is the most common histolojical pattern among primary testicular lymphomas. Although there is not a standart therapy especially for stage I and II disease, treatment with doksorubicinbased chemotherapy following orchiectomy is recommend in these stages. In advanced stages (III and IV), combination chemotherapy is the treatment of choise. Here, we report the case of a 69 -year- old man with primary testicular lymphoma and discuss the clinical features and treatment of this disease.
Abstract (Original Language): 
Primer testis non-Hodgkin lenfoması nadir görülen bir hastalıktır. Tüm testis malignitelerinin %1-9’unu oluşturur. Nadir görümesine rağmen, 60 yaşın üzerinde en sık görülen testis malignitesidir. En sık rastlanan histolojik tipi diffüz büyük B hücreli lenfomadır. Özellikle erken evre hastalıkta standart bir tedavi mevcut olmamakla birlikte, evre I ve II hastalıkta, orşiektomi sonrası doksorubisinli kemoterapi uygulaması önerilmektedir. İleri evre (evre III ve IV) hastalıkta kombinasyon kemoterapisi tercih edilen tedavi modalitesidir. Primer testis lenfomalı, 69 yaşındaki erkek hasta, hastalığın klinik özellikleri ve tedavi modaliteleri ile birlikte tartışmaya sunuldu.
57-59

REFERENCES

References: 

1. Shahab N, Doll DC: Testicular Lymphoma. Semin Oncol
1999;26(3):259-266.
2. Givler RL: Testicular involvement in leukemia and lymphoma.
Cancer 1969;.23:1290-1295.
3. Gospodarowicz MK, Zucca E: Primary testis lymphoma.
Presentation, treatment, patterns of failure and outcomes.
ASCO educational book. 2001; 281-285.
4. Ostronoff M, Soussain C, Zambon E, et al. Localized stage nonHodgkin’s lymphoma of the testis: A retrospective study of
16 cases. Nouv Rev Fr Hematol 1995; 267-272.
5. Duncan PR, Chea F, Gowing NF, Mc Elwain TJ, Peckham MS.
Extranodal non-Hodgkin’s lymphoma presenting in the
testicle. A clinical pathologic study of 24 cases. Cancer
1980; 45: 1578-1584.
6. Connors JM, Klimo P, Voss N, Fairey RN, Jackson S. Testicular
lymphoma: Improved outcome with early brief
chemotherapy. J Clin Oncol 1988; 6:776-781.
7. Zietman AL, Coen JJ, Ferry JA, Scully RE, Kaufman DS,
McGovern FG. The management and outcome of stage
IAE non-Hodgkin’s lymphoma of the testis. J Urol 1996;
155: 943-946.
8. Liang R, Chiu E, Loke SL. An analysis of 12 cases of nonHodgkin lymphomas involving the testis. Ann Oncol 1990;
1: 383.
9. Tourotoglou N, Dimopoulos MA, Younes A, et al. Testicular
lymphoma: Late relapses and poor outcome despite
doxorubicin based chemotherapy. J Clin Oncol 1995; 13:
1361-1367.
10. Lippuner T, Gosspodarowicz M, Pintilie M, et al. Testicular
lymphoma: Pattern of failure after long-term follow up.
VII. International Conference on Malignant Lymphoma,
Lugano, Switzerland. Ann Oncol 1999; 10: 63.
11. Fonseca R, Habermann TM, Colgan JP, et al. Testicular
lymphoma is associated with a high incidence of
extranodal recurrence. Cancer 2000; 88: 154-161.

Thank you for copying data from http://www.arastirmax.com