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Pineal Bölge Tümörleri

Pineal Region Tumors

Journal Name:

  • Uludağ Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2004

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
Pineal region tumors cover a large spectrum of benign and malignant tumor structures with multiple cell types. Germ cell tumors are more frequent in men and whereas the frequency of pineal cell tumors is equal in both sexes. Generally, obstructive type hydrocephalus accompanies this situation. As a result of this, increased intracranial pressure symptoms appear. MRI and germ cell markers are diagnostically valuable. Malignant germ cell or pineal cell tumors disseminate through CSF flow circulation into ventricles or spinal cord. The histological diagnosis should be made for the optimal treatment of pineal region tumors, because of the various tumor subtypes. Although current microsurgery techniques provide acceptable mortality and morbidity results, the surgical resection is difficult. The surgical intervention is curative for benign tumors and germ cell tumors and is positively correlated with the lifespan.
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Abstract (Original Language): 
Pineal bölge tümörleri; çok çeşitli hücre tiplerinin oluşturduğu benign ve malign tümör yapıları içeren geniş bir spektrumu içerir. Germ hücre tümörleri erkeklerde daha sık görülürken, pineal hücre tümörleri erkek ve kadınlarda eşit oranda görülür. Genellikle obstruktif tip hidrosefali ile birliktelik gösterir ve bu sebeple artmış intrakranial basınç semptomları ile ortaya çıkarlar. Tanıda genel değerlendirme MRG (magnetik rezonans görüntüleme) ve germ hücre belirteçleridir(alfa feto protein ve beta HCG). Malign germ hücreli veya pineal hücreli tümörler BOS akım yollarını izleyerek ventriküllere veya spinal korda yayılabilirler. Tümör subtiplerinin çeşitliliği sebebiyle pineal bölge tümörlerinin optimal klinik tedavisi için histolojik tanı mutlaka gereklidir. Mevcut mikrocerrahi teknikleri ile morbidite ve mortalite sonuçları kabul edilebilir düzeyde ise de cerrahi rezeksiyon güçtür. Cerrahi benign tümörler ve germ hücreli tümörler için genellikle küratiftir ve yaşam süresi ile pozitif korelasyon gösterir.
FULL TEXT (PDF): 
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  • 3
205-210
  • Turkish

REFERENCES

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