You are here

Home » Content

Çocuklarda H.pylori Enfeksiyonunda Seroloji, Tanı ve Tedavi

Journal Name:

  • Uludağ Üniversitesi Tıp Fakültesi Dergisi

Publication Year:

  • 2007

Key Words:

Keywords (Original Language):

Author NameUniversity of Author
Abstract (2. Language): 
H. pylori is a common infectious agent. In developing countries the individuals are infected frequently in relatively younger ages. Oraloral, gastric-oral and fecal-oral transmission is established. Household contacts, particularly infected mothers are known to spread the infection. Only in symptomatic cases, invasive and noninvasive tests are recommended for diagnosis of H.pylori. Although most of the infected children remain asymptomatic, H. pylori is a well-known reason of gastritis, recurrent abdominal pain and non-ulcer dyspepsia. The optimal therapeutic approach to H. pylori infection is not clear. But current suggestions indicate that the children with peptic ulcer and H. pylori infection should receive combined antibiotic (amoxicillin+ clarithromycine) and proton pump inhibitor therapy for 1-2 weeks.
Bookmark/Search this post with
Abstract (Original Language): 
H.pylori, dünya üzerinde yaygın ve sık olarak rastlanan bir enfeksiyon etkenidir. H.pylori enfeksiyonu, gelişmekte olan ülkelerde gelişmiş ülkelere göre daha sık ve daha erken yaşta görülmektedir. Bulaş şeklinin, insandan insana; oral-oral, gastrik-oral veya fekal-oral yollarla olabileceği bildirilmiştir. Enfeksiyonun aile içi bulaş ile yayıldığı, bu konuda enfekte annelerin daha çok bulaş nedeni olduğu bilinmektedir. H.pylori enfeksiyonunun saptanmasına yönelik noninvaziv ve invaziv testler ancak klinik semptomların varlığında önerilmektedir. Klinik çalışmaların sonuçlarına göre, H.pylori gastritinin çocuklarda büyük ölçüde asemptomatik kalabileceği kabul edilmiştir. Klasik klinik tablo gastritis, tekrarlayan karın ağrısı ve nonülser dispepsidir. Çocuklarda tedavi yaklaşımları net olmamakla birlikte peptik ülser ve H.pylori pozitifliği saptanan hastaların tedavi edilmesi önerilmektedir. Çocuklarda yeğlenen güncel tedavi; geniş spektrumlu ikili antibiyotik ve proton pompası inhibitörlerinin 1–2 hafta süreyle uygulanmasıdır.
FULL TEXT (PDF): 
PDF icon arastirmax-cocuklarda-h.pylori-enfeksiyonunda-seroloji-tani-tedavi.pdf
  • 2
81-85
  • Turkish

REFERENCES

References: 

1. Selimoglu MA, Ertekin V, Inandi T.Seroepidemiology of
Helicobacter pylori infection in children living in eastern
Turkey. Pediatr Int. 2002 Dec;44 (6):666–9.
2. Dore MP, Malaty HM, Graham DY. Risk Factors Associated
with Helicobacter pylori Infection among Children in a
Defined Geographic Area. Clin Infect Dis. 2002;35 (3):240–5
3. Ozen A, Ertem D, Pehlivanoglu E.Natural history and
symptomatology of Helicobacter pylori in childhood and
factors determining the epidemiology of infection. J Pediatr
Gastroenterol Nutr. 2006 Apr; 42 (4):398–404.
4. Malaty HM, Haveman T, Graham DY. Helicobacter pylori
infection in asymptomatic children: impact of epidemiologic
factors on accuracy of diagnostic tests. J Pediatr Gastroenterol
Nutr. 2002;35 (1):59–63.
5. Mitchell H, Megrasud F. Epidemiology and diagnosis of
Helicobacter pylori infection. Helicobacter 2002; 7 (Suppl
1):8-16.
6. Tindberg Y, Bengtson C, Granath F, Belennow M, Nyren O,
Granstrom M. Helicobacter pylori infection in Swedish school
children: lack of evidence of child-to child transmission
outside the family. Gastroenterology 2001; 121:310-316. Çocuklarda H.Pylori Enfeksiyonunda Seroloji
85
7. Rothenbacher D, Winkler M, Gonser T, Adler G, Brenner H.
Role of infected parents in transmission of Helicobacter pylori
to their children. Pediatr Infect Dis J 2002; 21:674-679.
8. Rothenbacter D, Bode G, Brenner H. History of breast feeding
and Helicobacter pylori infection in pre-school children:
results of a population-based study from Germany. Int J
Epidemial 2002; 31:632-637.
9. Kitagawa m, Natori M, Katoh M, et al. Maternal transmission
of Helicobacter pylori in the perinatal period. J Obstet
Gynaecol Res 2001; 27:255-230.
10. Okuda M, Miyashiro E, Koike M, Okuda J, Minami K,
Yoshikawa N. Breastfeeding prevents Helicobacter pylori
infection in early childhood. Pediatr Int 2001; 43:714-715.
11. Pearce M S, Thomas J E, Campbell D.I. Parker L. Does
increased duration of exclusive breast feeding protect against
Helicobacter pylori infection? The Newcastle thousand
families cohort study at age 49-51 years. Journal of Pediatric
Gastroenterology and Nutrition 2005; 41:617-20.
12. Gold BD, Khanna B, huang LM, Lee CY, Banat vala N.
Helicobacter pylori acquisition in infancy after decline of
maternal passive immunity. Pediatr Res 1997; 41:641-646.
13. Rowland M, Kumar D, Daly L, O’Conor P, Voughan D,
Drumm B. Low rates of Helicobacter pylori reinfection in
children. Gastroenterology 1999; 117:336-3341.
14. Koletzko S, Feydt-Schmidt A. Infants differ from teenagers:
use of non-invasive tests for detection of Helicobacter pylori
infection in children. Eur J Gastroenterol Hepatol 2001;
13:1047-1052.
15. Walters TD, Jones NL. Helicobacter pylori in childhood. In:
Wyllie R, Hyams JS (eds). Pediatric Gastrointestinal and
Liver Disease. 3th edtion. Philadelphia: Saunders. 2006:409–
437..
16. Jones NL, Sherman P, Fallone CA, et al. on behalf of the
Canadian Helicobacter Study Group. Consensus guidelines on
H.pylori infection in children and adolescents. Can J
Gastroenterol 2005.
17. El-Omar EM, Carrington M, Chow WH et al. Interleukin-1
polymorphisms associated with increased risk of gastric
cancer. Nature. 2000 Mar 23;404 (6776):398-402.
18. Roma E, Kafritsa Y, Panayiotou J, Liakou R, Constantopoulas
A. Is peptic ulcer a common cause of upper gastointestinal
symptoms? Eur J Pediatr 2001; 160: 497-500.
19. Ashorn M:What are the spesific features of Helicobacter
pylori gastritis in children? Ann Med 27: 617-620, 1995.
20. Roma E, Kafritsa Y, Panayiotou J, Is peptic ulcer a common
cause of upper gastrointestinal symptoms? Eur J Pediatr. 2001
Aug;160 (8):497–500.
21. Ozcay F, Gurakan F, Demir H et al. Helicobacter pylori
infection and reflux esophagitis in children.Helicobacter.
2002;7 (5):328–9.
22. Gottrand F Helicobacter pylori infection: what are the specific
questions in childhood? Gastroenterol Clin Biol. 2003 Mar;27
(3 Pt 2):484–7.
23. Baysoy G, Ertem D, Ademoglu E. Gastric histopathology,
iron status and iron deficiency anemia in children with
Helicobacter pylori infection. J Pediatr Gastroenterol Nutr.
2004 Feb;38 (2):146–51.
24. Bourke B, Ceponis P, Chiba N;Canadian Helicobacter Study
Group. Canadian Helicobacter Study Group Consensus
Conference: Update on the approach to Helicobacter pylori
infection in children and adolescents.Can J Gastroenterol.
2005;19 (7):399–408.
25. Oderda G, Marinello D, Lerro P, Kuvidi M, Angelis GL,
Ferzetti A, et al. Dual vs. Triple Therapy for Childhood
Helicobacter pylori Gastritis: A Double-Blind Randomized
Multicentre Trial. Helicobacter 2004; 9:293-301.
26. Rowland M, Imrie C, Bowke B, Drumm B. How should
Helicobacter pylori infected children be managed? Gut 1999;
4s (suppl 1): 163-139.
27. Dupont C, Kalach N, Raymond J. Helicobacter pylori and
antimicrobial susceptibility in children. J Pediatr Gastroenterol
Nutr 2003; 36:311-313.

Thank you for copying data from http://www.arastirmax.com