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Glukosinolatlar ve Hidroliz Ürünlerinin Kanser Türleri Üzerine Etkileri

The Effects of Glucosinolates and Their Hydrolysis Products on Cancer Types

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Abstract (2. Language): 
Brassicaceae species, together with being a very important material for nutrition; chemically, anticar-cinogenic, carcinogenic, antiestrogenic, estrogenic, antioxidant with antibiotic activity and inducing phase-II detoxification enzymes. Depending on the amount of these kinds of vegetables consumed by humans and animals, some ositive or negative metabolic effects of this molecule may occur. At the same time, liver, thyroid, kidney, stomach, colon, rectum abnormalities and development and reproductive performance can cause deterio-ration. ITCs inhibit mitosis and stimulate apoptosis in tumor cells.
Abstract (Original Language): 
Brassicaceae türleri, beslenme için çok önemli bir materyal olmakla birlikte; kanserojenik, antiöstrojenik, östrojenik, antibiyotik aktivitesi olan antioksidan ve faz-II detoksifikasyon enzimlerini tetikleyen kimyasal mad-deler içerir. İnsanlar ve hayvanlar tarafından tüketilen bu tür sebzelerin miktarına bağlı olarak, bu molekülün bazı olumlu veya olumsuz metabolik etkileri ortaya çıkabilir. Aynı zamanda karaciğer, tiroit, böbrek, mide, ko-lon, rektum anormallikleri ve gelişimi ve üreme performansının bozulmasına neden olabilir. İsothiosinolatlar, mitozu inhibe eder ve tümör hücrelerinde apoptozu uyarır.
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