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Melatonin ve Santral Sinir Sistemi

Melatonin and central nervous system

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Abstract (Original Language): 
1958'de Aaron B Lerner tarafından tanımlanan melatonin'in yaşlanma karşıtı etki, immîın düzenleyici, onkostatik ve nöroendokrin fonksiyonlar gibi pekçok fizyolojik fonksiyonları vardır. Son yıllarda melatonin 'in potent bir serbest hidroksil ve peroksil radikal tutucusu olduğu bildirilmektedir. Bu derleme yazıda, bir serbest radikal tutucusu olarak melatonin ve santral sinir sistemi patolojilerindeki rolünü inceledik. [Turgut Özal Tıp Merkezi Dergisi 1996;3(3):237-244J
Abstract (2. Language): 
The pineal hormon, Melatonin, which was described by Aaron B. Lerner in 1958, participitates in many important physiological functions including neuroendocrine, oncostatic, immune regulatory and anti-aging,. Recently, melatonin was reported to be a potent free radical scavenger, being more potent in scavenging hydroxyl andperoxyl radicals. In this report, we reviewed the melatonin as a scavenger and its role in CNSpathologies. [Journal of Turgut Özal Medical Center 1996;3(3):237-244]

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